What the FDA labels say about taking them together
Acetic acid and cyclosporine
Cyclosporine's FDA label (Sandimmune) of July 10, 2026 names acetic acid in its drug interactions section; the acetic acid labels PlainMeds reads (3) do not name cyclosporine. The cyclosporine label: “… decreases in renal function, as determined by 99m Tc-diethylenetriaminepenta acetic acid (DTPA) and p -aminohippuric acid (PAH) clearances.”
Check it at the source: the acetic acid FDA label on DailyMed (effective July 15, 2024); the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation).
What does the acetic acid label say about cyclosporine?
Acetic acid's label (effective July 15, 2024) and its 2 other brand-application labels do not name cyclosporine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Acetic Acid), NuCare Pharmaceuticals,Inc., effective July 15, 2024 (SPL set 7470a1ed-bc00-cb52-e053-2a91aa0a5c7d), via openFDA; the full label on DailyMed
What does the cyclosporine label say about acetic acid?
Sandimmune label (Novartis Pharmaceuticals Corporation, July 10, 2026), drug interactionsPharmacodynamic interactions have been reported to occur between cyclosporine and both naproxen and sulindac, in that concomitant use is associated with additive decreases in renal function, as determined by 99m Tc-diethylenetriaminepenta acetic acid (DTPA) and p -aminohippuric acid (PAH) clearances.
Source: FDA drug label (Sandimmune, NDA050573), Novartis Pharmaceuticals Corporation, effective July 10, 2026 (SPL set 5e5926a7-1de0-4b54-a5c0-286b6200ff82), via openFDA
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Acetic acid | Cyclosporine | |
|---|---|---|
| Labeled for | n/a | Organ transplant rejection, Rheumatoid arthritis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.49 per mL 2% ear solution | $1.04 per unit 0.05% eye emulsion |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once