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What the FDA labels say about taking them together

Acetazolamide and quinine

Quinine's FDA label of November 9, 2023 names acetazolamide in its drug interactions (prescription label) section; the acetazolamide label PlainMeds reads does not name quinine. The quinine label: “Urinary Alkalizers Urinary alkalinizing agents may increase plasma quinine concentrations.”

Check it at the source: the acetazolamide FDA label on DailyMed (effective August 19, 2026, Strides Pharma Science Limited); the quinine FDA label on DailyMed (effective November 9, 2023).

What does the acetazolamide label say about quinine?

Acetazolamide's label (effective August 19, 2026) does not name quinine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Acetazolamide), Strides Pharma Science Limited, effective August 19, 2026 (SPL set 4813b9dd-5f58-44bb-ad64-cdb331828080), via openFDA; the full label on DailyMed

What does the quinine label say about acetazolamide?

Quinine label, drug interactions (prescription label)

Urinary Alkalizers (Acetazolamide, Sodium Bicarbonate) Urinary alkalinizing agents may increase plasma quinine concentrations.

Source: FDA drug label (Chininum sulphuricum), Boiron, effective November 9, 2023 (SPL set 33885950-2a55-11e7-8288-424c58303031), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

38Acetazolamide generic labelers
4Quinine generic labelers
AcetazolamideQuinine
Labeled forn/an/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.134 per tablet 250 mg tablet$0.698 per capsule 324 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?