What the FDA labels say about taking them together
Acetazolamide and dextroamphetamine
Dextroamphetamine's FDA label of November 26, 2025 names acetazolamide in its drug interactions section; the acetazolamide label PlainMeds reads does not name dextroamphetamine. The dextroamphetamine label: “Urinary alkalinizing agents increase the concentration of the non-ionized species of the amphetamine molecule, thereby decreasing urinary excretion.”
Check it at the source: the acetazolamide FDA label on DailyMed (effective August 19, 2026, Strides Pharma Science Limited); the dextroamphetamine FDA label on DailyMed (effective November 26, 2025, Azurity Pharmaceuticals, Inc.).
What does the acetazolamide label say about dextroamphetamine?
Acetazolamide's label (effective August 19, 2026) does not name dextroamphetamine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Acetazolamide), Strides Pharma Science Limited, effective August 19, 2026 (SPL set 4813b9dd-5f58-44bb-ad64-cdb331828080), via openFDA; the full label on DailyMed
What does the dextroamphetamine label say about acetazolamide?
Dextroamphetamine label, drug interactionsUrinary alkalinizing agents (acetazolamide, some thiazides) increase the concentration of the non-ionized species of the amphetamine molecule, thereby decreasing urinary excretion.
Source: FDA drug label (Zenzedi), Azurity Pharmaceuticals, Inc., effective November 26, 2025 (SPL set d6394df5-f2c9-47eb-b57e-f3e9cfd94f84), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Acetazolamide | Dextroamphetamine | |
|---|---|---|
| Labeled for | n/a | ADHD |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.134 per tablet 250 mg tablet | $0.373 per tablet 10 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once