What the FDA labels say about taking them together
Acetaminophen and lomitapide
Lomitapide's FDA label of March 30, 2026 names acetaminophen in its warnings and precautions section; the acetaminophen labels PlainMeds reads (4) do not name lomitapide.
Check it at the source: the acetaminophen FDA label on DailyMed (effective November 13, 2024, Kenvue Brands LLC); the lomitapide FDA label on DailyMed (effective March 30, 2026, Chiesi USA, Inc.).
What does the acetaminophen label say about lomitapide?
Acetaminophen's label (effective November 13, 2024) and its 3 other brand-application labels do not name lomitapide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Tylenol 8 HR Arthritis Pain), Kenvue Brands LLC, effective November 13, 2024 (SPL set 3af22fc8-e4e0-4863-8696-6bc1257047cb), via openFDA; the full label on DailyMed
What does the lomitapide label say about acetaminophen?
Lomitapide label, warnings and precautionsExercise caution when using JUXTAPID with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen.
Source: FDA drug label (Juxtapid), Chiesi USA, Inc., effective March 30, 2026 (SPL set 61a0be9d-ee58-43e0-b5cb-141011835081), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Acetaminophen | Lomitapide | |
|---|---|---|
| Labeled for | Fever, Cough and cold, Pain | High cholesterol |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.0339 per unit 500 mg caplet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once