What the FDA labels say about taking them together
Acalabrutinib and calcium carbonate
Acalabrutinib's FDA label (Calquence) of February 19, 2026 names calcium carbonate in its drug interactions section; the calcium carbonate label PlainMeds reads does not name acalabrutinib.
Check it at the source: the acalabrutinib FDA label on DailyMed (effective February 19, 2026, AstraZeneca Pharmaceuticals LP); the calcium carbonate FDA label on DailyMed (effective December 5, 2024).
What does the acalabrutinib label say about calcium carbonate?
Calquence label (AstraZeneca Pharmaceuticals LP, February 19, 2026), drug interactionsIf treatment with a gastric acid reducing agent is required, consider using a H2‑receptor antagonist (e.g., ranitidine or famotidine) or an antacid (e.g., calcium carbonate).
Source: FDA drug label (Calquence, NDA210259), AstraZeneca Pharmaceuticals LP, effective February 19, 2026 (SPL set dd4835ef-e1bc-4997-a399-1ffa2556fbfe), via openFDA
Source: FDA drug label (CALQUENCE), AstraZeneca Pharmaceuticals LP, effective February 19, 2026 (SPL set b1409184-3267-4d8c-8f17-4e01f69828b1), via openFDA; the full label on DailyMed
What does the calcium carbonate label say about acalabrutinib?
Calcium carbonate's label (effective December 5, 2024) does not name acalabrutinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (TUMS EX), Haleon US Holdings LLC, effective December 5, 2024 (SPL set 593a0494-d669-4bcf-8412-b92645b2d76c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Acalabrutinib | Calcium carbonate | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0315 per tablet 750 mg tablet chewable |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once