What the FDA labels say about taking them together
Abemaciclib and ketoconazole
Abemaciclib's FDA label of July 13, 2026 names ketoconazole in its drug interactions section; the ketoconazole label PlainMeds reads does not name abemaciclib. The abemaciclib label: “DRUG INTERACTIONS CYP3A Inhibitors: Avoid concomitant use of ketoconazole.”
Check it at the source: the abemaciclib FDA label on DailyMed (effective July 13, 2026, Eli Lilly and Company); the ketoconazole FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC).
What does the abemaciclib label say about ketoconazole?
Abemaciclib label, drug interactionsDRUG INTERACTIONS CYP3A Inhibitors: Avoid concomitant use of ketoconazole.
Source: FDA drug label (Verzenio), Eli Lilly and Company, effective July 13, 2026 (SPL set be4bc0de-0fdc-4d46-8d25-be43c79e6a06), via openFDA; the full label on DailyMed
What does the ketoconazole label say about abemaciclib?
Ketoconazole's label (effective January 28, 2026) does not name abemaciclib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ketoconazole), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set cad7c647-34a9-4e4e-83b3-8d78e58f588f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Abemaciclib | Ketoconazole | |
|---|---|---|
| Labeled for | Breast cancer | Fungal infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.249 per gram 2% cream |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once