What the FDA labels say about taking them together
Abacavir/dolutegravir/lamivudine and riociguat
Abacavir/dolutegravir/lamivudine's FDA label of July 8, 2024 names riociguat in its drug interactions section; the riociguat label PlainMeds reads does not name abacavir/dolutegravir/lamivudine. The abacavir/dolutegravir/lamivudine label: “Riociguat Abacavir: Coadministration with TRIUMEQ resulted in increased riociguat exposure, which may increase the risk of riociguat adverse reactions.”
Check it at the source: the abacavir/dolutegravir/lamivudine FDA label on DailyMed (effective July 8, 2024, ViiV Healthcare Company); the riociguat FDA label on DailyMed (effective August 13, 2026, Bayer HealthCare Pharmaceuticals Inc.).
What does the abacavir/dolutegravir/lamivudine label say about riociguat?
Abacavir/dolutegravir/lamivudine label, drug interactionsRiociguat Abacavir: Coadministration with TRIUMEQ resulted in increased riociguat exposure, which may increase the risk of riociguat adverse reactions [see Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Triumeq), ViiV Healthcare Company, effective July 8, 2024 (SPL set 2997739a-aa91-42aa-a206-a70e2db7b84f), via openFDA; the full label on DailyMed
What does the riociguat label say about abacavir/dolutegravir/lamivudine?
Riociguat's label (effective August 13, 2026) does not name abacavir/dolutegravir/lamivudine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Adempas), Bayer HealthCare Pharmaceuticals Inc., effective August 13, 2026 (SPL set 7b57509a-3d5d-41d4-8fed-1471e26372a3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Abacavir/dolutegravir/lamivudine | Riociguat | |
|---|---|---|
| Labeled for | HIV | Pulmonary arterial hypertension |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $130.01 per tablet 600-50-300 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once