Zenocutuzumab Brand names: Bizengri

What is zenocutuzumab used for?

From the label: indications and usage

BIZENGRI® is a bispecific HER2- and HER3-directed antibody indicated for the treatment of: Adults with advanced, unresectable or metastatic non-small cell lung cancer (NSCLC) harboring a neuregulin 1 ( NRG1 ) gene fusion with disease progression on or after prior systemic therapy.* ( 1.1 ) Adults with advanced, unresectable or metastatic pancreatic adenocarcinoma harboring a neuregulin 1 ( NRG1 ) gene fusion with disease progression on or after prior systemic therapy.* ( 1.2 ) Adults with advanced, unresectable or metastatic cholangiocarcinoma harboring a neuregulin 1 ( NRG1 ) gene fusion with disease progression on or after prior systemic therapy. […]

Conditions named in the indications of zenocutuzumab's FDA labels, with every medicine labeled for each:

• Lung cancer

From other zenocutuzumab labels

Lung cancer: Unresectable or Metastatic NRG1 Fusion-Positive Non-Small Cell Lung Cancer BIZENGRI is indicated for the treatment of adults with advanced unresectable or metastatic non-small cell lung cancer (NSCLC) harboring a neuregulin 1 ( NRG1 ) gene …

What does the patient leaflet for zenocutuzumab say first?

The FDA-approved Medication Guide or Patient Information that comes with the medicine, in its own words.

From the patient leaflet: What is the most important information I should know about BIZENGRI?

BIZENGRI can cause serious side effects, including: Infusion-related, allergic and anaphylactic reactions. BIZENGRI can cause serious infusion-related and allergic reactions that can be life-threatening. Infusion-related reactions are also common during BIZENGRI treatment. Before each BIZENGRI infusion, your healthcare provider will give you medicines to help reduce your chance of getting infusion-related reactions. Your healthcare provider will monitor you for signs and symptoms during your infusion and for at least 1 hour after your first infusion and as needed. Tell your healthcare provider right away if you develop any of the following signs or symptoms during or after your BIZENGRI infusion: chills or shaking nausea, vomiting, or diarrhea fever cough sudden swelling of your face, tongue, throat, or troubled swallowing throat tightness or discomfort itching or rash shortness of breath or wheezing chest discomfort feeling light-headed dizziness back or neck pain feeling of numbness or tingling Lung problems. BIZENGRI can cause serious lung problems that may be life-threatening. If you develop lung problems, your healthcare provider may treat you with corticosteroid medicines. Tell your healthcare provider right away if you develop any new or worsening symptoms of lung problems, including: trouble breathing shortness of breath cough fever Heart problems that may affect your heart's ability to pump blood. BIZENGRI can cause serious and life-threatening heart problems that may lead to death. Your healthcare provider will check your heart function before you start treatment with BIZENGRI and as needed during your treatment. […]

Is there a generic for zenocutuzumab (Bizengri)?

No generic zenocutuzumab is approved (Drugs@FDA, October 8, 2026).

What does the zenocutuzumab label say about other medicines?

The zenocutuzumab label names 1 other medicine in its interaction, contraindication or warning sections. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.

Check zenocutuzumab against other medicines

What do FAERS reports show for zenocutuzumab?

The FDA Adverse Event Reporting System holds 8 reports that list zenocutuzumab among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 1 are coded as a death and 1 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

The most reported reactions

• Drug Ineffective (a use or a product term, not a reaction)2
• Dysphonia2
• Cardio-Respiratory Distress1
• Diarrhoea (named in the label)1
• Disease Progression (a use or a product term, not a reaction)1
• Drug Intolerance1
• Infusion Related Reaction (named in the label)1
• Off Label Use (a use or a product term, not a reaction)1

What else is labeled for the same conditions as zenocutuzumab?

16 other medicines are given the same way (intravenous) and in the same FDA class as zenocutuzumab or labeled mainly for the same use (lung cancer), the same class first. Lung cancer lists all 55 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.

Every medicine labeled for the same conditions as zenocutuzumab

What next?

Alternatives to zenocutuzumab

16 medicines for the same use

Zenocutuzumab side effects

the label's list beside FAERS reports

Check an interaction

what two or more labels say about each other