Prescription medicine

Donor human stool spores Brand names: Vowst

Donor human stool spores (Vowst) is a prescription medicine. No generic is listed in FDA's NDC Directory.

No generic listed

Check it at the source: the donor human stool spores FDA label on DailyMed (effective April 23, 2026); every donor human stool spores label on DailyMed.

Highlights of the record

FDA label of April 23, 2026; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026

Used for

From the label: indications and usage
VOWST is indicated to prevent the recurrence of Clostridioides difficile infection (CDI) in individuals 18 years of age and older following antibacterial treatment for recurrent CDI (rCDI).

Forms and strengths

Capsule.

On the market

Generic approvals: No generic approved
Labelers listed (NDC): 1 of which 0 under generic applications, 1 under brand applications, repackagers included

Supply and safety

Pharmacy cost (NADAC): Not in the survey
Shortage (FDA): No current entry
Recalls by its makers (FDA): No recall recorded
FAERS reports: 1,163 through July 30, 2026

What is donor human stool spores used for?

From the label: indications and usage
VOWST is indicated to prevent the recurrence of Clostridioides difficile infection (CDI) in individuals 18 years of age and older following antibacterial treatment for recurrent CDI (rCDI). VOWST is indicated to prevent the recurrence of Clostridioides difficile infection (CDI) in individuals 18 years of age and older following antibacterial treatment for recurrent CDI (rCDI). ( 1 ) Limitation of Use: VOWST is not indicated for treatment of CDI. Limitation of Use: VOWST is not indicated for treatment of CDI.

Source: FDA drug label (VOWST), Aimmune Therapeutics, Inc., effective April 23, 2026 (SPL set 99e5a37a-930c-4641-bcdd-7013ec1c15fe), via openFDA; the full label on DailyMed

Is there a generic for donor human stool spores (Vowst)?

No generic donor human stool spores is approved (Drugs@FDA, October 8, 2026).

Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)

What do FAERS reports show for donor human stool spores?

The FDA Adverse Event Reporting System holds 1,163 reports that list donor human stool spores among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 13 are coded as a death and 97 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

Reports received each year

The most reported reactions

Diarrhoea (named in the label)549
Clostridium Difficile Infection327
Clostridium Test Positive145
Abdominal Pain106
Nausea (named in the label)90
Constipation (named in the label)80
Drug Ineffective (a use or a product term, not a reaction)80
Abdominal Distension (named in the label)74

Side effects: the label's list and every FAERS reaction

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026

What next?

Donor human stool spores side effects: the label's list beside FAERS reports
Check an interaction: what two or more labels say about each other