Over-the-counter medication · Topical NSAID
diclofenac topical
Also sold as Voltaren Gel, Pennsaid. This medicine is for temporary relief of arthritis pain.
Data updated 2026-05-15
- $21.42
- Brand price (NADAC)
diclofenac topical (Voltaren Gel) is an over-the-counter Topical NSAID. This medicine is for temporary relief of arthritis pain.
Diclofenac topical gel is a medicine that helps relieve arthritis pain. It belongs to a class of drugs called topical NSAIDs.
Verify with FDA → · CMS NADAC pricing →
Drug Pricing (NADAC)
Brand Price
$21.42/unit
Generic Available
Yes (2 manufacturers)
Pricing data from NADAC (CMS), effective November 20, 2024. Compare all drug costs →
What it does
This medicine is for temporary relief of arthritis pain.
Common side effects
No common side effects listed.
Key warnings
Do not use this medicine for strains, sprains, bruises, or sports injuries.
The sections below are summarized in plain English from diclofenac topical's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.
How It Works
Diclofenac is an NSAID that reduces inflammation and pain. When applied to the skin, it is absorbed into the tissues. This reduces pain and swelling in the treated area.
Serious Warnings
Do not use this medicine for strains, sprains, bruises, or sports injuries. This medicine has not been shown to work for these types of injuries. Only apply to clean, dry skin without cuts, wounds, infections, or rashes. Do not use with heat or bandages.
Common Questions
How much gel should I use?
Can I use a heating pad with this gel?
Can I bandage the area after applying the gel?
What should I do if I accidentally use too much gel?
Can I use this gel on my back pain?
How long should I use the gel for?
Can I use this gel on open wounds?
What should I do if I don't feel any relief after using the gel for a week?
Can I use this with other topical products?
Where should I store the dosing card?
What drug class is diclofenac topical?
What pregnancy or breastfeeding source fields are listed for diclofenac topical?
Related Medications in Topical NSAID
Other drugs grouped near diclofenac topical - same-class peers and common alternatives.
abatacept
Orencia
Orencia is a medicine that helps to reduce inflammation.
Compare with diclofenac topical →
acetaminophen
Tylenol
Acetaminophen (Tylenol) is a medicine that can relieve pain and reduce fever.
Compare with diclofenac topical →
acetaminophen/hydrocodone
Vicodin, Norco
This medicine contains acetaminophen and hydrocodone.
Compare with diclofenac topical →
acetaminophen/oxycodone
Percocet
Percocet is a strong pain medicine.
Compare with diclofenac topical →
adalimumab
Humira
Idacio is a medicine that blocks a protein called TNF.
Compare with diclofenac topical →
Medication Guides
Understanding Drug Interactions
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Generic vs Brand Name Drugs
FDA requirements, cost savings, and when the difference matters
Pain Relievers Compared
NSAIDs vs acetaminophen, which OTC pain reliever to use
Narrow Therapeutic Index Drugs
FDA bioequivalence and label-record context for narrow therapeutic index medicines
Common Drug Interactions
Dangerous medication combinations and how to protect yourself
What the FDA Data Shows for diclofenac topical
The FDA label for diclofenac topical (sold under brand names such as Voltaren Gel, Pennsaid) classifies it as an over-the-counter product in the Topical NSAID class. This medicine is for temporary relief of arthritis pain. Labeling covers dosing, contraindications, and monitoring requirements derived from clinical trials.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. Voluntary reports accumulate over the lifetime of a drug and reflect wide-ranging clinical use. Interaction data is drawn directly from FDA-approved prescribing information. NADAC pricing from CMS.
Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information are separate source-record fields. This page is a public FDA/CMS registry and does not provide medical, treatment, substitution, or medication-change directions.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. This registry does not provide medication decisions.
Last updated: July 29, 2024
PlainMeds is rendered directly from FDA openFDA/FAERS extracts, DailyMed labels, and CMS drug-pricing files, no number is typed in by an editor. FAERS counts, recalls, shortages, and price figures on this page are queried live from those federal extracts. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-05-15. Primary sources: openFDA / FAERS, DailyMed and CMS Part B ASP.
Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled from the source snapshot dated . See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a data issue.
All federal data sources used on this page
- FDA Orange Book - approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed - NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) - post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm - standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files - federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database - current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages