Prescription medication · Immunosuppressant (Ophthalmic)

cyclosporine ophthalmic

Also sold as Restasis, Cequa. VEVYE treats dry eye disease.

Data updated 2026-05-15

$9.38
Brand price (NADAC)

cyclosporine ophthalmic (Restasis) is a prescription Immunosuppressant (Ophthalmic). VEVYE treats dry eye disease.

VEVYE eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.

Drug Pricing (NADAC)

Brand Price

$9.38/unit

Generic Available

No

Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →

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What it does

VEVYE treats dry eye disease.

Common side effects

Irritation where the drop is applied

Key warnings

To avoid injury or contamination, do not touch your eye or other surfaces with the bottle tip.

The sections below are summarized in plain English from cyclosporine ophthalmic's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.

How It Works

VEVYE contains cyclosporine, which is a type of medicine that lowers your body's immune response in the eye. It reduces inflammation. This helps your eyes make more tears.

Serious Warnings

To avoid injury or contamination, do not touch your eye or other surfaces with the bottle tip. Do not use VEVYE while wearing contact lenses. If you wear contacts, take them out before using the drops. You can put them back in 15 minutes after using the drops.

Common Questions

What is the strength of VEVYE?
VEVYE contains 0.1% cyclosporine.
How often should I use VEVYE?
Use one drop in each eye twice a day.
Can I use VEVYE with my contact lenses?
No, remove your contact lenses before using VEVYE. You can put them back in 15 minutes after using the drops.
What should I do if the bottle tip touches my eye?
Try to avoid touching your eye with the bottle tip to prevent injury or contamination.
How should I store VEVYE?
Store VEVYE at room temperature, away from heat and light.
What if I accidentally swallow VEVYE?
VEVYE is for eye use only. If swallowed, contact your doctor or poison control center.
Can I use VEVYE if I am pregnant?
Talk to your doctor if you are pregnant or planning to become pregnant before using VEVYE.
Can I use VEVYE if I am breastfeeding?
Talk to your doctor if you are breastfeeding before using VEVYE.
What should I do if I experience blurry vision after using VEVYE?
Temporary blurry vision is a less common side effect. If it persists or worsens, contact your doctor.
How long can I use VEVYE after opening the bottle?
You can use VEVYE until the expiration date on the bottle, even after opening it.
What are the common side effects of cyclosporine ophthalmic?
The registry lists Irritation where the drop is applied among the most-reported FAERS reaction terms for cyclosporine ophthalmic. These counts are not an individual symptom assessment.
What drug class is cyclosporine ophthalmic?
cyclosporine ophthalmic belongs to the Immunosuppressant (Ophthalmic) drug class. It requires a prescription (Rx). VEVYE treats dry eye disease.
What pregnancy or breastfeeding source fields are listed for cyclosporine ophthalmic?
The FDA label for cyclosporine ophthalmic contains product-specific pregnancy or breastfeeding language. PlainMeds does not apply that source text to an individual.

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What the FDA Data Shows for cyclosporine ophthalmic

The FDA label for cyclosporine ophthalmic (sold under brand names such as Restasis, Cequa) classifies it as a prescription-only medication in the Immunosuppressant (Ophthalmic) class. VEVYE treats dry eye disease. Official labeling lists 1 commonly reported side effect, including Irritation where the drop is applied.

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. Voluntary reports accumulate over the lifetime of a drug and reflect wide-ranging clinical use. Interaction data is drawn directly from FDA-approved prescribing information. NADAC pricing from CMS.

Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information are separate source-record fields. This page is a public FDA/CMS registry and does not provide medical, treatment, substitution, or medication-change directions.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. This registry does not provide medication decisions.

Last updated: November 14, 2025

PlainMeds is rendered directly from FDA openFDA/FAERS extracts, DailyMed labels, and CMS drug-pricing files, no number is typed in by an editor. FAERS counts, recalls, shortages, and price figures on this page are queried live from those federal extracts. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-05-15. Primary sources: openFDA / FAERS, DailyMed and CMS Part B ASP.

Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled from the source snapshot dated . See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a data issue.

All federal data sources used on this page