cyclosporine ophthalmic
Brand names: Restasis, Cequa
VEVYE eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.
Drug Pricing (NADAC)
Brand Price
$9.38/unit
Generic Available
No
Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →
What it does
VEVYE treats dry eye disease.
Common side effects
Irritation where the drop is applied
Key warnings
To avoid injury or contamination, do not touch your eye or other surfaces with the bottle tip.
How It Works
VEVYE contains cyclosporine, which is a type of medicine that lowers your body's immune response in the eye. It reduces inflammation. This helps your eyes make more tears.
How to Take It
Wash your hands before using VEVYE. Put one drop in each eye twice a day, about 12 hours apart. Gently pull down your lower eyelid and let one drop fall into your eye. If you use other eye drops, wait 15 minutes between them.
Pregnancy & Breastfeeding
It is not known if VEVYE can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if VEVYE passes into breast milk, so talk to your doctor if you are breastfeeding.
Missed Dose
If you miss a dose of VEVYE, use it as soon as you remember. Then, continue with your regular schedule.
Storage
Store VEVYE at room temperature (59°F to 77°F). Do not freeze or refrigerate.
Serious Warnings
To avoid injury or contamination, do not touch your eye or other surfaces with the bottle tip. Do not use VEVYE while wearing contact lenses. If you wear contacts, take them out before using the drops. You can put them back in 15 minutes after using the drops.
Common Questions
What is the strength of VEVYE?
How often should I use VEVYE?
Can I use VEVYE with my contact lenses?
What should I do if the bottle tip touches my eye?
How should I store VEVYE?
What if I accidentally swallow VEVYE?
Can I use VEVYE if I am pregnant?
Can I use VEVYE if I am breastfeeding?
What should I do if I experience blurry vision after using VEVYE?
How long can I use VEVYE after opening the bottle?
What are the common side effects of cyclosporine ophthalmic?
What drug class is cyclosporine ophthalmic?
Is cyclosporine ophthalmic safe during pregnancy?
Related Medications in Immunosuppressant (Ophthalmic)
Other drugs grouped near cyclosporine ophthalmic — same-class peers and common alternatives.
aflibercept
Eylea
AHZANTIVE is a medicine used to treat certain eye problems.
Compare with cyclosporine ophthalmic →
artificial tears
Refresh, Systane
Artificial tears are eye drops that lubricate your eyes.
Compare with cyclosporine ophthalmic →
bevacizumab (ophthalmic)
Avastin
Avastin is a medicine that blocks a protein called vascular endothelial growth factor (VEGF).
Compare with cyclosporine ophthalmic →
bimatoprost
Lumigan
Bimatoprost eye drops help lower pressure in the eye.
Compare with cyclosporine ophthalmic →
brimonidine ophthalmic
Alphagan P
Alphagan P eye drops help lower pressure in the eye.
Compare with cyclosporine ophthalmic →
Compare cyclosporine ophthalmic vs aflibercept side-by-side →
Medication Guides
Understanding Drug Interactions
How CYP450 enzymes, inhibitors, and inducers affect your medications
Generic vs Brand Name Drugs
FDA requirements, cost savings, and when the difference matters
Narrow Therapeutic Index Drugs
Why some drugs demand precise dosing and monitoring
Common Drug Interactions
Dangerous medication combinations and how to protect yourself
Related Health & Safety Data
🩺 Find a Doctor
Search prescribers for Immunosuppressant (Ophthalmic)
🏨 Hospital Quality
CMS hospital ratings, safety scores & patient outcomes
💊 Supplement Data
NIH DSLD — check supplement ingredients & label claims
🍽️ Food Safety Alerts
FDA recalls, inspections & outbreak investigations
⚠️ Product Recalls
FDA, CPSC & NHTSA recall search
💉 Procedure Costs
Medicare procedure pricing for 9,297 procedures
Save on cyclosporine ophthalmic
Compare prices and find discounts at pharmacies near you. Free coupons can save up to 80% on prescriptions.
Disclosure: This link may earn us a commission at no extra cost to you. See our terms.
What the FDA Data Shows for cyclosporine ophthalmic
The FDA label for cyclosporine ophthalmic (sold under brand names such as Restasis, Cequa) classifies it as a prescription-only medication in the Immunosuppressant (Ophthalmic) class. VEVYE treats dry eye disease. Official labeling lists 1 commonly reported side effect, including Irritation where the drop is applied.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. Voluntary reports accumulate over the lifetime of a drug and reflect wide-ranging clinical use. Interaction data is drawn directly from FDA-approved prescribing information. NADAC pricing from CMS.
Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.
Last updated: November 14, 2025
Read our methodology — how this data is sourced, computed, and verified.
All federal data sources used on this page
- FDA Orange Book — approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed — NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) — post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm — standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files — federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database — current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages