Prescription medication · Immunosuppressant (Ophthalmic)
cyclosporine ophthalmic
Also sold as Restasis, Cequa. VEVYE treats dry eye disease.
Data updated 2026-05-15
- $9.38
- Brand price (NADAC)
cyclosporine ophthalmic (Restasis) is a prescription Immunosuppressant (Ophthalmic). VEVYE treats dry eye disease.
VEVYE eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.
Verify with FDA → · CMS NADAC pricing →
Drug Pricing (NADAC)
Brand Price
$9.38/unit
Generic Available
No
Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →
What it does
VEVYE treats dry eye disease.
Common side effects
Irritation where the drop is applied
Key warnings
To avoid injury or contamination, do not touch your eye or other surfaces with the bottle tip.
The sections below are summarized in plain English from cyclosporine ophthalmic's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.
How It Works
VEVYE contains cyclosporine, which is a type of medicine that lowers your body's immune response in the eye. It reduces inflammation. This helps your eyes make more tears.
How to Take It
Wash your hands before using VEVYE. Put one drop in each eye twice a day, about 12 hours apart. Gently pull down your lower eyelid and let one drop fall into your eye. If you use other eye drops, wait 15 minutes between them.
This is a plain-language summary of cyclosporine ophthalmic's FDA labeling, not individualized dosing advice. Ask a pharmacist or prescriber before changing how you take this medication.
Pregnancy & Breastfeeding
It is not known if VEVYE can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if VEVYE passes into breast milk, so talk to your doctor if you are breastfeeding.
This is a plain-language summary of cyclosporine ophthalmic's FDA labeling, not individualized advice. Ask a pharmacist or prescriber about pregnancy or breastfeeding on this medication.
Missed Dose
If you miss a dose of VEVYE, use it as soon as you remember. Then, continue with your regular schedule.
This is a plain-language summary of cyclosporine ophthalmic's FDA labeling, not individualized advice. Ask a pharmacist or prescriber what to do about your specific missed dose.
Storage
Store VEVYE at room temperature (59°F to 77°F). Do not freeze or refrigerate.
Serious Warnings
To avoid injury or contamination, do not touch your eye or other surfaces with the bottle tip. Do not use VEVYE while wearing contact lenses. If you wear contacts, take them out before using the drops. You can put them back in 15 minutes after using the drops.
Common Questions
What is the strength of VEVYE?
How often should I use VEVYE?
Can I use VEVYE with my contact lenses?
What should I do if the bottle tip touches my eye?
How should I store VEVYE?
What if I accidentally swallow VEVYE?
Can I use VEVYE if I am pregnant?
Can I use VEVYE if I am breastfeeding?
What should I do if I experience blurry vision after using VEVYE?
How long can I use VEVYE after opening the bottle?
What are the common side effects of cyclosporine ophthalmic?
What drug class is cyclosporine ophthalmic?
Is cyclosporine ophthalmic safe during pregnancy?
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What the FDA Data Shows for cyclosporine ophthalmic
The FDA label for cyclosporine ophthalmic (sold under brand names such as Restasis, Cequa) classifies it as a prescription-only medication in the Immunosuppressant (Ophthalmic) class. VEVYE treats dry eye disease. Official labeling lists 1 commonly reported side effect, including Irritation where the drop is applied.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. Voluntary reports accumulate over the lifetime of a drug and reflect wide-ranging clinical use. Interaction data is drawn directly from FDA-approved prescribing information. NADAC pricing from CMS.
Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice, always consult a licensed healthcare provider before starting, stopping, or changing any medication.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.
Last updated: November 14, 2025
Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled and last refreshed May 2026. See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a correction.
All federal data sources used on this page
- FDA Orange Book - approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed - NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) - post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm - standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files - federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database - current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages