Prescription medicine
Cenegermin Brand names: Oxervate
Cenegermin (Oxervate) is a prescription medicine. No generic is listed in FDA's NDC Directory.
- No generic listed
Check it at the source: the cenegermin FDA label on DailyMed (effective December 31, 2024); every cenegermin label on DailyMed.
Highlights of the record
FDA label of December 31, 2024; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026
Used for
From the label: indications and usageOXERVATE ® (cenegermin-bkbj) ophthalmic solution 0.002% is indicated for the treatment of neurotrophic keratitis.
Forms and strengths
Solution/ drops; kit.
On the market
- Generic approvals
- No generic approved
- Labelers listed (NDC)
- 1 of which 0 under generic applications, 1 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- Not in the survey
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- No recall recorded
- FAERS reports
- 12,024 through July 30, 2026
What is cenegermin used for?
From the label: indications and usageOXERVATE ® (cenegermin-bkbj) ophthalmic solution 0.002% is indicated for the treatment of neurotrophic keratitis. OXERVATE is a recombinant human nerve growth factor indicated for the treatment of neurotrophic keratitis.
FDA pharmacologic class: Recombinant Human Nerve Growth Factor.
Source: FDA drug label (OXERVATE), Domp farmaceutici S.p.A., effective December 31, 2024 (SPL set 89e4bfec-d710-40ed-8885-5d13ba46b1cd), via openFDA; the full label on DailyMed
What does the patient leaflet for cenegermin say first?
The FDA-approved Medication Guide or Patient Information that comes with the medicine, in its own words.
From the patient leaflet: What should I avoid while using OXERVATE?Your vision may be blurred for a short time after using OXERVATE. If this happens, wait until your vision clears before you drive or use machines.
Source: FDA drug label (OXERVATE), Domp farmaceutici S.p.A., effective December 31, 2024 (SPL set 89e4bfec-d710-40ed-8885-5d13ba46b1cd), via openFDA; the full label on DailyMed
Is there a generic for cenegermin (Oxervate)?
No generic cenegermin is approved (Drugs@FDA, October 8, 2026).
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do FAERS reports show for cenegermin?
The FDA Adverse Event Reporting System holds 12,024 reports that list cenegermin among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 211 are coded as a death and 780 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is. Reports rose sharply in 2025 (3,179, against a median of 661 a year): FAERS counts follow reporting, which news, litigation and label changes can drive, not how often a reaction happens.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What next?
- Cenegermin side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other