Prescription medicine
Amcinonide First approved as Cyclocort
Amcinonide (Cyclocort) is a prescription medicine with an FDA approval on record since 1979. FDA's NDC Directory lists it from 3 generic labelers, and pharmacies paid $4.90 per gram (Amcinonide 0.1% cream) in the October 7, 2026 NADAC survey.
- Generic listed
Check it at the source: the amcinonide FDA label on DailyMed (effective April 3, 2025, Sun Pharmaceutical Industries, Inc.); the NDA 18116 record on Drugs@FDA; every amcinonide label on DailyMed.
Highlights of the record
FDA label of April 3, 2025; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026
Used for
From the label: indications and usageTopical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Forms and strengths
- 1 mg/g
Ointment; cream.
On the market
- Earliest approval on file
- October 18, 1979 Cyclocort, Astellas; Drugs@FDA’s file, where older or withdrawn approvals can be missing
- Generic approvals
- 5 first May 31, 2002; 3 with a marketed status in Drugs@FDA
- Labelers listed (NDC)
- 3 of which 3 under generic applications, 0 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- $4.90 per gram Amcinonide 0.1% cream
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- No recall recorded
- FAERS reports
- 85 through July 30, 2026
What is amcinonide used for?
From the label: indications and usageTopical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
FDA pharmacologic class: Corticosteroid.
Source: FDA drug label (Amcinonide), Sun Pharmaceutical Industries, Inc., effective April 3, 2025 (SPL set ac5c3e79-52f7-434e-92ae-24bd32b45edc), via openFDA; the full label on DailyMed
Is there a generic for amcinonide (Cyclocort)?
The FDA approved the first generic amcinonide on May 31, 2002. 5 generic applications are approved; 3 of them carry a current (not discontinued) marketing status in Drugs@FDA; that status is not evidence that the generic is on sale.
FDA's NDC Directory lists amcinonide from 3 labelers under a generic (ANDA) application. A listing means the company has registered the product for sale; it does not show that every pharmacy stocks it.
- 1979 earliest approval on file
- 2002 first generic approved
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do pharmacies pay for amcinonide (Cyclocort)?
In CMS's NADAC survey of October 7, 2026, pharmacies paid $4.90 per gram (Amcinonide 0.1% cream), down 56% from $11.13 on October 8, 2025. The survey records the price, not the reason for a change; large moves often follow a new generic or a list-price change. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.
- Amcinonide 0.1% cream (generic)
| Strength and form | Brand or generic | Pharmacy cost | 30 tablets, or one pen or vial | 12-month change |
|---|---|---|---|---|
| Amcinonide 0.1% cream | Generic | $4.90 per gram | n/a | -56% |
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What do FAERS reports show for amcinonide?
The FDA Adverse Event Reporting System holds 85 reports that list amcinonide among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 13 are coded as a death and 24 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What next?
- Other corticosteroids
- the pharmacologic class, with prices and generics
- Amcinonide side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other