LOW-VOLUME · SEX-BALANCED
zaleplon Side Effects
zaleplon (also sold as Sonata) is a LOW-VOLUME FAERS extract #473 of 524 by FAERS report count. Still opens on SEX-BALANCED: 68% of sex-coded reports are female (979 F / 462 M).
Data updated 2026-05-15
- 1,538
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
zaleplon reporting skew - 68% of sex-coded reports are female (979 F / 462 M). Volume band LOW-VOLUME #473 of 524 by FAERS report count; caseload SIGNAL.
Thinner FAERS extract for zaleplon (Sonata) (1,538 reports #473 of 524 by FAERS report count). 68% of sex-coded reports are female (979 F / 462 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
NAUSEA leads 111 of 1,538 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (406 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (173 reports, 11.2%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 88 |
| TOXICITY TO VARIOUS AGENTS | 29 |
| DEATH | 27 |
| CARDIAC ARREST | 10 |
| OVERDOSE | 9 |
| INTENTIONAL PRODUCT MISUSE | 8 |
| PNEUMONIA | 8 |
| SUSPECTED SUICIDE | 6 |
| INSOMNIA | 5 |
| RENAL FAILURE | 5 |
| RESPIRATORY FAILURE | 5 |
| CHRONIC KIDNEY DISEASE | 4 |
| ABNORMAL BEHAVIOUR | 3 |
| ACUTE KIDNEY INJURY | 3 |
| ASPIRATION | 3 |
| BRAIN OEDEMA | 3 |
| DEPRESSION | 3 |
| DRUG TOXICITY | 3 |
| FALL | 3 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 3 |
Reactions in Hospitalization Reports
Hospitalization mid-share (338, 22.0%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| FALL | 33 |
| PNEUMONIA | 22 |
| ACUTE KIDNEY INJURY | 21 |
| NAUSEA | 19 |
| RENAL FAILURE | 19 |
| URINARY TRACT INFECTION | 19 |
| CHRONIC KIDNEY DISEASE | 17 |
| HYPOTENSION | 17 |
| INSOMNIA | 17 |
| SOMNOLENCE | 17 |
| PAIN | 16 |
| TOXICITY TO VARIOUS AGENTS | 16 |
| ANXIETY | 15 |
| COMPLETED SUICIDE | 15 |
| DYSPNOEA | 15 |
| SINUSITIS | 15 |
| VOMITING | 15 |
| DIZZINESS | 14 |
| OVERDOSE | 14 |
| DIARRHOEA | 13 |
How to read zaleplon FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-MID)
FAERS holds 1,538 voluntary reports linked to zaleplon (Sonata), 2004-2025. Death is listed on 173 (11.2%). Hospitalization appears on 338 (22.0%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with zaleplon
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 1,541 FAERS cases (Δ 3 heavier vs zaleplon); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 1,547 FAERS cases (Δ 9 heavier vs zaleplon); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 1,527 FAERS cases (Δ 11 lighter vs zaleplon); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 1,551 FAERS cases (Δ 13 heavier vs zaleplon); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 50.9 pp vs zaleplon's DEATH-HEAVY): CASELOAD · HOSP-MID.
zaleplon stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.