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What the label lists and what reports show

Vasopressin side effects

Vasopressin's FDA label: “The most common adverse reactions include decreased cardiac output, bradycardia, tachyarrhythmias, hyponatremia and ischemia (coronary, mesenteric, skin, digital).” FAERS holds 4,355 reports naming it through July 30, 2026; the reaction reported most often, leaving out the conditions it is used for, product-use terms and outcomes, is hypotension (508 reports).

  • Generic listed

Check it at the source: the vasopressin FDA label on DailyMed (effective February 21, 2025, Baxter Healthcare Corporation); the FDA FAERS public dashboard.

What does the label list?

From the label: adverse reactions

The most common adverse reactions include decreased cardiac output, bradycardia, tachyarrhythmias, hyponatremia and ischemia (coronary, mesenteric, skin, digital).

From the label: adverse reactions, continued

The following adverse reactions associated with the use of vasopressin were identified in the literature. Because these reactions are reported voluntarily from a population of uncertain size, it is not possible to estimate reliably their frequency or establish a causal relationship to drug exposure. Bleeding/lymphatic system disorders: Hemorrhagic shock, decreased platelets, intractable bleeding Cardiac disorders: Right heart failure, atrial fibrillation, bradycardia, myocardial ischemia Gastrointestinal disorders: Mesenteric ischemia Hepatobiliary: Increased bilirubin levels Renal/urinary disorders: Acute renal insufficiency Vascular disorders: Distal limb ischemia Metabolic: Hyponatremia Skin: Ischemic lesions Postmarketing Experience Reversible diabetes insipidus [ see Warnings and Precautions (5.2) ] The most common adverse reactions include decreased cardiac output, bradycardia, tachyarrhythmias, hyponatremia and ischemia (coronary, mesenteric, skin, digital). ( 6 ) To report SUSPECTED ADVERSE REACTIONS, contact Baxter Healthcare at 1-866-888-2472 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Source: FDA drug label, Baxter Healthcare Corporation, effective February 21, 2025 (SPL set b5b2c367-6b7e-40be-a296-c4632f3e783f), via openFDA; the full label on DailyMed

What do FAERS reports show?

4,355 reports list vasopressin among the medicines taken, each a report of something that happened, not proof the medicine caused it; 1,717 are coded as a death and 2,520 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is. Of the 20 reactions below, 1 is named by the same term (in US spelling) in the label's adverse reactions, warnings or patient leaflet; a reaction the label does not name may still be there under another word, and a report does not show that the medicine caused it.

Reports received each year

The 25 most reported reactions

  • Drug Ineffective (a use or a product term, not a reaction)1,333
  • Off Label Use (a use or a product term, not a reaction)545
  • Hypotension508
  • Cardiogenic Shock418
  • Multiple Organ Dysfunction Syndrome409
  • Sepsis404
  • Condition Aggravated (a use or a product term, not a reaction)392
  • Toxicity To Various Agents338
  • Acute Kidney Injury333
  • Stress310
  • Vomiting310
  • Abdominal Pain289
  • General Physical Health Deterioration286
  • Ascites282
  • Hyponatraemia (named in the label)281
  • Nausea279
  • Abdominal Distension275
  • Cardiac Arrest267
  • Appendicitis259
  • Constipation259
  • Appendicolith257
  • Intentional Overdose (a use or a product term, not a reaction)232
  • Ventricular Fibrillation231
  • Death (an outcome recorded in the report)230
  • Renal Failure219

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; reactions as MedDRA preferred terms

What next?

Vasopressin: the full record
label, generics, price, shortages, recalls
Side effects hub
the most reported medicines and reactions