Drug side effects
vasopressin Side Effects
The reactions most often reported to the FDA for vasopressin (also sold as Vasostrict), with demographics, serious outcomes, and reporting trends.
Data updated 2026-05-15
- 4,135
- FAERS reports
Data from the FDA Adverse Event Reporting System (FAERS), 2004 to 2025. A FAERS report records a temporal association, not proof of cause. See our methodology for how figures are compiled and de-duplicated.
The most commonly reported side effects of vasopressin come from 4,135 reports to the FDA, broken down here by frequency, patient demographics, and serious outcomes.
This page analyzes 4,135 reports to the FDA Adverse Event Reporting System (FAERS) for vasopressin (Vasostrict): the reactions reported most often, who reported them, serious outcomes such as hospitalization, and year-over-year trends. A FAERS report does not prove the drug caused the effect, and report volume tracks how widely a drug is used, not how likely an effect is for any one person. Educational information, not medical advice.
Total Reports
4,135
Reports Mentioning Death
1,633
39.5% of reports — not proof the medicine caused the death
Hospitalizations
2,378
57.5% of reports
Top Indication
Product Used For Unknown Indication
Most Reported Adverse Reactions
Who Reports Side Effects
Gender Distribution
Age Distribution
Reporting Trend by Year
Reactions in Death Reports
Top reactions reported in 1,633 reports where death was an outcome. These are voluntarily reported and do not establish causation.
| Reaction | Reports |
|---|---|
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 354 |
| SEPSIS | 338 |
| CARDIOGENIC SHOCK | 273 |
| STRESS | 262 |
| VOMITING | 256 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 248 |
| ASCITES | 247 |
| ABDOMINAL DISTENSION | 243 |
| ABDOMINAL PAIN | 241 |
| NAUSEA | 239 |
| HYPONATRAEMIA | 237 |
| APPENDICITIS | 234 |
| APPENDICOLITH | 233 |
| CONDITION AGGRAVATED | 232 |
| CONSTIPATION | 230 |
| DEATH | 217 |
| VENTRICULAR FIBRILLATION | 205 |
| HYPOTENSION | 185 |
Reactions in Hospitalization Reports
Top reactions in 2,378 reports where hospitalization was an outcome.
| Reaction | Reports |
|---|---|
| HYPOTENSION | 344 |
| TOXICITY TO VARIOUS AGENTS | 268 |
| CONDITION AGGRAVATED | 253 |
| CARDIOGENIC SHOCK | 237 |
| ACUTE KIDNEY INJURY | 216 |
| INTENTIONAL OVERDOSE | 203 |
| SEPSIS | 201 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 199 |
| CARDIAC ARREST | 164 |
| VOMITING | 164 |
| LACTIC ACIDOSIS | 145 |
| ABDOMINAL PAIN | 142 |
| SOMNOLENCE | 138 |
| NAUSEA | 136 |
| OVERDOSE | 136 |
| SHOCK | 134 |
| ANAEMIA | 133 |
| STRESS | 131 |
Nearby, Related Medications
What the FAERS Data Reveals About vasopressin Side Effects
The FDA Adverse Event Reporting System (FAERS) contains 4,135 voluntary reports linked to vasopressin and its brand equivalents (Vasostrict), spanning 2004 through 2025. Of those, 1,633 (39.5%) listed death as an outcome and 2,378 (57.5%) involved hospitalization. The most common indication reported alongside adverse events was Product Used For Unknown Indication.
Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 42% were female and 57% male; age distribution skews toward 45-64, with 1,251 reports in that bracket. The single most reported reaction is hypotension with 486 submissions, followed by cardiogenic shock and sepsis.
How to read these numbers
FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice, speak with a licensed clinician about any side-effect concerns.
Drugs With a Similar FAERS Report Volume
Other medications with a total FDA adverse-event report count closest to vasopressin's 4,135.
Read our methodology - how this data is sourced, computed, and verified.