MID-VOLUME · HOSP-HEAVY
trimethoprim Side Effects
trimethoprim (also sold as Primsol) sits MID-VOLUME #303 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 43.7% mention hospitalization (4,968 reports). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 11,380
- FAERS reports
FDA Adverse Event Reporting System extract for trimethoprim. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.
trimethoprim: 43.7% mention hospitalization (4,968 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #303 of 524 by FAERS report count.
Mid-book FAERS page for trimethoprim (Primsol) (11,380 reports). Signature HOSP-HEAVY. Dominant age band on file: 75+. Educational reference only.
Counts from the openFDA FAERS extract (2001–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 945 of 11,380 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (2,547 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (1,472 reports, 12.9%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 241 |
| DIARRHOEA | 217 |
| DYSPNOEA | 180 |
| VOMITING | 177 |
| PNEUMONIA | 175 |
| MALAISE | 172 |
| LOWER RESPIRATORY TRACT INFECTION | 166 |
| PYREXIA | 157 |
| CONDITION AGGRAVATED | 156 |
| INFECTION | 141 |
| DECREASED APPETITE | 139 |
| ASTHENIA | 136 |
| FATIGUE | 135 |
| INFLAMMATION | 133 |
| HYPERTENSION | 132 |
| NAUSEA | 128 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 127 |
| RASH | 125 |
| ABDOMINAL PAIN | 124 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (4,968, 43.7% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| PYREXIA | 556 |
| DIARRHOEA | 555 |
| MALAISE | 547 |
| NAUSEA | 516 |
| VOMITING | 496 |
| DYSPNOEA | 423 |
| ACUTE KIDNEY INJURY | 418 |
| URINARY TRACT INFECTION | 372 |
| HEADACHE | 369 |
| PAIN | 368 |
| ABDOMINAL PAIN | 360 |
| CONFUSIONAL STATE | 348 |
| FATIGUE | 330 |
| PNEUMONIA | 323 |
| DIZZINESS | 320 |
| RASH | 289 |
| WEIGHT DECREASED | 285 |
| CONDITION AGGRAVATED | 274 |
How to read trimethoprim FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 11,380 voluntary reports linked to trimethoprim (Primsol), 2001-2025. Death is listed on 1,472 (12.9%). Hospitalization appears on 4,968 (43.7%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 43.7% mention hospitalization (4,968 reports).
Read with trimethoprim
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 11,382 FAERS cases (Δ 2 heavier vs trimethoprim); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 11,311 FAERS cases (Δ 69 lighter vs trimethoprim); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 11,257 FAERS cases (Δ 123 lighter vs trimethoprim); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 11,247 FAERS cases (Δ 133 lighter vs trimethoprim); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 49.2 pp vs trimethoprim's DEATH-HEAVY): CASELOAD · HOSP-MID.
trimethoprim stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.