LOW-VOLUME · HOSP-HEAVY
pyridoxine Side Effects
pyridoxine (also sold as Vitamin B6) is a LOW-VOLUME FAERS extract #442 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 46.3% mention hospitalization (1,129 reports).
Data updated 2026-05-15
- 2,439
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
pyridoxine: 46.3% mention hospitalization (1,129 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #442 of 524 by FAERS report count.
Thinner FAERS extract for pyridoxine (Vitamin B6) (2,439 reports #442 of 524 by FAERS report count). 46.3% mention hospitalization (1,129 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 389 of 2,439 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (533 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (501 reports, 20.5%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| VOMITING | 240 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 239 |
| ABDOMINAL DISTENSION | 223 |
| ABDOMINAL PAIN | 216 |
| ASCITES | 212 |
| APPENDICITIS | 211 |
| APPENDICOLITH | 210 |
| CONSTIPATION | 207 |
| NAUSEA | 207 |
| SEPSIS | 206 |
| HYPONATRAEMIA | 204 |
| CARDIOGENIC SHOCK | 202 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 198 |
| STRESS | 189 |
| CONDITION AGGRAVATED | 182 |
| VENTRICULAR FIBRILLATION | 171 |
| DRY MOUTH | 164 |
| SWELLING | 145 |
| BLOOD CHOLESTEROL INCREASED | 144 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (1,129, 46.3% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| NAUSEA | 216 |
| VOMITING | 215 |
| SOMNOLENCE | 200 |
| CONDITION AGGRAVATED | 196 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 177 |
| DRUG HYPERSENSITIVITY | 169 |
| FATIGUE | 166 |
| GASTROOESOPHAGEAL REFLUX DISEASE | 166 |
| SWELLING | 165 |
| ABDOMINAL PAIN | 161 |
| DIARRHOEA | 157 |
| BLOOD CHOLESTEROL INCREASED | 156 |
| DYSPNOEA | 156 |
| DRY MOUTH | 153 |
| PAIN | 152 |
| ABDOMINAL DISTENSION | 142 |
| SLEEP DISORDER | 138 |
How to read pyridoxine FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 2,439 voluntary reports linked to pyridoxine (Vitamin B6), 2004-2025. Death is listed on 501 (20.5%). Hospitalization appears on 1,129 (46.3%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with pyridoxine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 2,450 FAERS cases (Δ 11 heavier vs pyridoxine); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 2,425 FAERS cases (Δ 14 lighter vs pyridoxine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 2,415 FAERS cases (Δ 24 lighter vs pyridoxine); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 2,477 FAERS cases (Δ 38 heavier vs pyridoxine); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 41.6 pp vs pyridoxine's DEATH-HEAVY): CASELOAD · HOSP-MID.
pyridoxine stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.