LOW-VOLUME · SEX-BALANCED
protriptyline Side Effects
protriptyline (also sold as Vivactil) is a LOW-VOLUME FAERS extract #519 of 524 by FAERS report count. Still opens on SEX-BALANCED: 68% of sex-coded reports are female (61 F / 29 M).
Data updated 2026-05-15
- 96
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
protriptyline reporting skew - 68% of sex-coded reports are female (61 F / 29 M). Volume band LOW-VOLUME #519 of 524 by FAERS report count; caseload TRACE-CASE.
Thinner FAERS extract for protriptyline (Vivactil) (96 reports #519 of 524 by FAERS report count). 68% of sex-coded reports are female (61 F / 29 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2012–2025). Stamps TRACE-CASE · DEATH-RARE · HOSP-MID · SEX-BALANCED.
FALL leads 12 of 96 reports
Who reports · age peak 18-44 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 18-44 (14 reports)
FAERS filings rising toward 2025
Reactions in Hospitalization Reports
Hospitalization mid-share (24, 25.0%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| FALL | 5 |
| HOSPITALISATION | 4 |
| ILLNESS | 3 |
| PRODUCT ADMINISTRATION INTERRUPTED | 3 |
| ABDOMINAL DISCOMFORT | 2 |
| ANXIETY | 2 |
| CONDITION AGGRAVATED | 2 |
| DIZZINESS | 2 |
| DYSPNOEA | 2 |
| HEAD INJURY | 2 |
| HYPERTENSION | 2 |
| HYPOGLYCAEMIA | 2 |
| INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION | 2 |
| LOSS OF CONSCIOUSNESS | 2 |
| MUSCLE SPASMS | 2 |
| OSTEOARTHRITIS | 2 |
| PAIN | 2 |
| SEIZURE | 2 |
| VOMITING | 2 |
| WITHDRAWAL SYNDROME | 2 |
How to read protriptyline FAERS figures (TRACE-CASE · DEATH-RARE · HOSP-MID)
FAERS holds 96 voluntary reports linked to protriptyline (Vivactil), 2012-2025. No death outcome in this extract. Hospitalization appears on 24 (25.0%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with protriptyline
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-RARE · HOSP-MID stamps.
ABS(total_reports) peer at 108 FAERS cases (Δ 12 heavier vs protriptyline); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-RARE · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 81 FAERS cases (Δ 15 lighter vs protriptyline); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's TRACE-CASE · DEATH-RARE · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 73 FAERS cases (Δ 23 lighter vs protriptyline); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's TRACE-CASE · DEATH-RARE · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 67 FAERS cases (Δ 29 lighter vs protriptyline); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-RARE · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 62.1 pp vs protriptyline's DEATH-RARE): CASELOAD · HOSP-MID.
protriptyline stamps TRACE-CASE · SEX-BALANCED; class peers and methodology beat restating the same FAERS caveats on every effects URL.