MID-VOLUME · SEX-BALANCED
paliperidone Side Effects
paliperidone (also sold as Invega) sits MID-VOLUME #222 of 524 by FAERS report count. Lead signal: SEX-BALANCED - 32% of sex-coded reports are female (5,980 F / 12,927 M). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 22,775
- FAERS reports
FDA Adverse Event Reporting System extract for paliperidone. Stamp set WATCHLIST · DEATH-MARKED · HOSP-MID. How figures are compiled.
paliperidone reporting skew - 32% of sex-coded reports are female (5,980 F / 12,927 M). Volume band MID-VOLUME #222 of 524 by FAERS report count; caseload WATCHLIST.
Mid-book FAERS page for paliperidone (Invega) (22,775 reports). Signature SEX-BALANCED. Dominant age band on file: 18-44. Educational reference only.
Counts from the openFDA FAERS extract (2007–2025). Stamps WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
INJURY leads 4,331 of 22,775 reports
Who reports · age peak 18-44 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 18-44 (5,235 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death appears on 801 reports (3.5% - MARKED). Reactions below co-occur in those rows only.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 213 |
| DEATH | 153 |
| TOXICITY TO VARIOUS AGENTS | 107 |
| SCHIZOPHRENIA | 52 |
| DYSTONIA | 47 |
| BLOOD GLUCOSE INCREASED | 45 |
| DYSKINESIA | 45 |
| SEDATION | 45 |
| SUICIDE ATTEMPT | 45 |
| CONDITION AGGRAVATED | 44 |
| METABOLIC DISORDER | 43 |
| ANOSOGNOSIA | 42 |
| BLOOD PROLACTIN ABNORMAL | 42 |
| DISTURBANCE IN SOCIAL BEHAVIOUR | 42 |
| SEXUAL DYSFUNCTION | 42 |
| PERSONALITY CHANGE | 41 |
| ADVERSE DRUG REACTION | 34 |
| OVERDOSE | 32 |
Reactions in Hospitalization Reports
Hospitalization mid-share (4,563, 20.0%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| HOSPITALISATION | 492 |
| SCHIZOPHRENIA | 250 |
| TREATMENT NONCOMPLIANCE | 245 |
| PSYCHOTIC DISORDER | 236 |
| WEIGHT INCREASED | 210 |
| NEUROLEPTIC MALIGNANT SYNDROME | 196 |
| EXTRAPYRAMIDAL DISORDER | 191 |
| TACHYCARDIA | 187 |
| SOMNOLENCE | 184 |
| DRUG INTERACTION | 183 |
| TREMOR | 182 |
| SUICIDE ATTEMPT | 179 |
| CONFUSIONAL STATE | 176 |
| OVERDOSE | 163 |
| AGGRESSION | 161 |
| ANXIETY | 155 |
| CONDITION AGGRAVATED | 146 |
| SUICIDAL IDEATION | 145 |
How to read paliperidone FAERS figures (WATCHLIST · DEATH-MARKED · HOSP-MID)
FAERS holds 22,775 voluntary reports linked to paliperidone (Invega), 2007-2025. Death is listed on 801 (3.5%). Hospitalization appears on 4,563 (20.0%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-MARKED · HOSP-MID as signal-detection rates next to 32% of sex-coded reports are female (5,980 F / 12,927 M).
Read with paliperidone
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.
ABS(total_reports) peer at 22,750 FAERS cases (Δ 25 lighter vs paliperidone); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 22,556 FAERS cases (Δ 219 lighter vs paliperidone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 23,037 FAERS cases (Δ 262 heavier vs paliperidone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 23,107 FAERS cases (Δ 332 heavier vs paliperidone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 58.6 pp vs paliperidone's DEATH-MARKED): CASELOAD · HOSP-MID.
paliperidone stamps WATCHLIST · SEX-BALANCED; class peers and methodology beat restating the same FAERS caveats on every effects URL.