LOW-VOLUME · FEMALE-LED
nortriptyline Side Effects
nortriptyline (also sold as Pamelor) is a LOW-VOLUME FAERS extract #387 of 524 by FAERS report count. Still opens on FEMALE-LED: 76% of sex-coded reports are female (3,671 F / 1,179 M).
Data updated 2026-05-15
- 5,503
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
nortriptyline reporting skew - 76% of sex-coded reports are female (3,671 F / 1,179 M). Volume band LOW-VOLUME #387 of 524 by FAERS report count; caseload WATCHLIST.
Thinner FAERS extract for nortriptyline (Pamelor) (5,503 reports #387 of 524 by FAERS report count). 76% of sex-coded reports are female (3,671 F / 1,179 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
PAIN leads 695 of 5,503 reports
FEMALE-LED reporters · age peak 45-64
Female-led reporters (76% of sex-coded rows)
Age peak 45-64 (1,575 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (674 reports, 12.2%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 203 |
| OVERDOSE | 131 |
| PAIN | 110 |
| TOXICITY TO VARIOUS AGENTS | 110 |
| HYPERTENSION | 105 |
| PYREXIA | 104 |
| THROMBOCYTOPENIA | 104 |
| FATIGUE | 103 |
| CONSTIPATION | 101 |
| PSORIASIS | 101 |
| DEATH | 100 |
| UPPER RESPIRATORY TRACT INFECTION | 99 |
| CONTRAINDICATED PRODUCT ADMINISTERED | 98 |
| HEADACHE | 98 |
| HYPERHIDROSIS | 98 |
| TEMPERATURE REGULATION DISORDER | 98 |
Reactions in Hospitalization Reports
Hospitalization mid-share (1,439, 26.1%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| SOMNOLENCE | 226 |
| GASTROOESOPHAGEAL REFLUX DISEASE | 214 |
| COMA | 199 |
| PNEUMONIA ASPIRATION | 195 |
| PAIN | 175 |
| NAUSEA | 170 |
| FATIGUE | 148 |
| DIARRHOEA | 146 |
| FALL | 133 |
| PAIN IN EXTREMITY | 129 |
| HEADACHE | 117 |
| ARTHRALGIA | 102 |
| SLEEP DISORDER | 99 |
| OSTEOARTHRITIS | 96 |
| DEPRESSION | 92 |
| OSTEOPENIA | 90 |
| DYSPNOEA | 89 |
| DIZZINESS | 88 |
How to read nortriptyline FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-MID)
FAERS holds 5,503 voluntary reports linked to nortriptyline (Pamelor), 2004-2025. Death is listed on 674 (12.2%). Hospitalization appears on 1,439 (26.1%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and FEMALE-LED skew still differ by drug; not a complete safety profile.
Read with nortriptyline
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 5,460 FAERS cases (Δ 43 lighter vs nortriptyline); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 5,567 FAERS cases (Δ 64 heavier vs nortriptyline); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 5,342 FAERS cases (Δ 161 lighter vs nortriptyline); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 5,762 FAERS cases (Δ 259 heavier vs nortriptyline); DEATH-MARKED · HOSP-LIGHT · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 49.9 pp vs nortriptyline's DEATH-HEAVY): CASELOAD · HOSP-MID.
nortriptyline stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.