LOW-VOLUME · SEX-BALANCED
diflunisal Side Effects
diflunisal (also sold as Dolobid) is a LOW-VOLUME FAERS extract #497 of 524 by FAERS report count. Still opens on SEX-BALANCED: 70% of sex-coded reports are female (470 F / 206 M).
Data updated 2026-05-15
- 799
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
diflunisal reporting skew - 70% of sex-coded reports are female (470 F / 206 M). Volume band LOW-VOLUME #497 of 524 by FAERS report count; caseload SIGNAL.
Thinner FAERS extract for diflunisal (Dolobid) (799 reports #497 of 524 by FAERS report count). 70% of sex-coded reports are female (470 F / 206 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
NAUSEA leads 66 of 799 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (186 reports)
Reporting taper since 2004 peak
Reactions in Death Reports
Death-mentioned subset is HEAVY here (66 reports, 8.3%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 25 |
| DEATH | 13 |
| CARDIAC ARREST | 10 |
| CARDIO-RESPIRATORY ARREST | 7 |
| RESPIRATORY ARREST | 7 |
| TOXICITY TO VARIOUS AGENTS | 5 |
| CARDIAC FAILURE | 4 |
| EYE DISORDER | 4 |
| PNEUMONIA | 4 |
| RASH | 4 |
| RESPIRATORY DISORDER | 4 |
| TOXIC EPIDERMAL NECROLYSIS | 4 |
| CONDITION AGGRAVATED | 3 |
| FALL | 3 |
| GASTROINTESTINAL HAEMORRHAGE | 3 |
| PAIN | 3 |
| SEPSIS | 3 |
| ACUTE HEPATIC FAILURE | 2 |
| ACUTE KIDNEY INJURY | 2 |
Reactions in Hospitalization Reports
Hospitalization mid-share (236, 29.5%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| FALL | 21 |
| NAUSEA | 20 |
| PNEUMONIA | 19 |
| DIARRHOEA | 18 |
| PAIN | 18 |
| VOMITING | 16 |
| CHEST PAIN | 15 |
| FATIGUE | 14 |
| MALAISE | 14 |
| HEADACHE | 13 |
| PLATELET COUNT DECREASED | 13 |
| BLOOD CREATININE INCREASED | 12 |
| ARTHRALGIA | 11 |
| BACK PAIN | 11 |
| DIZZINESS | 10 |
| DYSPNOEA | 10 |
| ACUTE MYOCARDIAL INFARCTION | 9 |
| CARDIAC FAILURE | 9 |
| CARDIAC PACEMAKER INSERTION | 9 |
How to read diflunisal FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-MID)
FAERS holds 799 voluntary reports linked to diflunisal (Dolobid), 2004-2025. Death is listed on 66 (8.3%). Hospitalization appears on 236 (29.5%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with diflunisal
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 774 FAERS cases (Δ 25 lighter vs diflunisal); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 826 FAERS cases (Δ 27 heavier vs diflunisal); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 834 FAERS cases (Δ 35 heavier vs diflunisal); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 762 FAERS cases (Δ 37 lighter vs diflunisal); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 53.8 pp vs diflunisal's DEATH-HEAVY): CASELOAD · HOSP-MID.
diflunisal stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.