LOW-VOLUME · HOSP-HEAVY
clomipramine Side Effects
clomipramine (also sold as Anafranil) is a LOW-VOLUME FAERS extract #399 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 54.0% mention hospitalization (2,376 reports).
Data updated 2026-05-15
- 4,403
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
clomipramine: 54.0% mention hospitalization (2,376 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #399 of 524 by FAERS report count.
Thinner FAERS extract for clomipramine (Anafranil) (4,403 reports #399 of 524 by FAERS report count). 54.0% mention hospitalization (2,376 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (1998–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DRUG INTERACTION leads 225 of 4,403 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (1,216 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (393 reports, 8.9%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 56 |
| COMPLETED SUICIDE | 38 |
| CARDIAC ARREST | 26 |
| CARDIO-RESPIRATORY ARREST | 25 |
| PYREXIA | 23 |
| TOXICITY TO VARIOUS AGENTS | 20 |
| DYSPNOEA | 18 |
| VOMITING | 18 |
| INTENTIONAL OVERDOSE | 17 |
| COMA | 16 |
| DRUG INTERACTION | 16 |
| DEPRESSED LEVEL OF CONSCIOUSNESS | 15 |
| NAUSEA | 15 |
| AGITATION | 14 |
| PNEUMONIA | 14 |
| SEPTIC SHOCK | 14 |
| PNEUMONIA ASPIRATION | 13 |
| SUDDEN DEATH | 13 |
| TOXIC EPIDERMAL NECROLYSIS | 13 |
| FOETAL EXPOSURE DURING PREGNANCY | 12 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (2,376, 54.0% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| FALL | 167 |
| DRUG INTERACTION | 144 |
| SUICIDE ATTEMPT | 138 |
| TREMOR | 132 |
| CONFUSIONAL STATE | 124 |
| INTENTIONAL OVERDOSE | 121 |
| SOMNOLENCE | 117 |
| COMA | 97 |
| ASTHENIA | 95 |
| OVERDOSE | 93 |
| PYREXIA | 89 |
| TOXICITY TO VARIOUS AGENTS | 89 |
| SOPOR | 88 |
| DRUG ABUSE | 86 |
| LOSS OF CONSCIOUSNESS | 86 |
| NAUSEA | 85 |
| TACHYCARDIA | 85 |
| HYPOTENSION | 84 |
| DEPRESSION | 83 |
How to read clomipramine FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 4,403 voluntary reports linked to clomipramine (Anafranil), 1998-2025. Death is listed on 393 (8.9%). Hospitalization appears on 2,376 (54.0%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with clomipramine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 4,286 FAERS cases (Δ 117 lighter vs clomipramine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 4,224 FAERS cases (Δ 179 lighter vs clomipramine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 4,213 FAERS cases (Δ 190 lighter vs clomipramine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 4,175 FAERS cases (Δ 228 lighter vs clomipramine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 53.2 pp vs clomipramine's DEATH-HEAVY): CASELOAD · HOSP-MID.
clomipramine stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.