MID-VOLUME · HOSP-HEAVY
chlorthalidone Side Effects
chlorthalidone (also sold as Thalitone) sits MID-VOLUME #308 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 32.5% mention hospitalization (3,583 reports). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 11,035
- FAERS reports
FDA Adverse Event Reporting System extract for chlorthalidone. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.
chlorthalidone: 32.5% mention hospitalization (3,583 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #308 of 524 by FAERS report count.
Mid-book FAERS page for chlorthalidone (Thalitone) (11,035 reports). Signature HOSP-HEAVY. Dominant age band on file: 45-64. Educational reference only.
Counts from the openFDA FAERS extract (2004–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
FATIGUE leads 861 of 11,035 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (2,757 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (656 reports, 5.9%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 274 |
| COMPLETED SUICIDE | 54 |
| ACUTE KIDNEY INJURY | 48 |
| PNEUMONIA | 43 |
| RENAL FAILURE | 39 |
| CHRONIC KIDNEY DISEASE | 37 |
| DYSPNOEA | 33 |
| HYPOTENSION | 33 |
| TOXICITY TO VARIOUS AGENTS | 32 |
| FATIGUE | 29 |
| CARDIAC ARREST | 27 |
| END STAGE RENAL DISEASE | 26 |
| FALL | 22 |
| MYOCARDIAL INFARCTION | 19 |
| SEPSIS | 18 |
| COUGH | 17 |
| COAGULOPATHY | 16 |
| URINARY TRACT INFECTION | 16 |
| ANAEMIA | 15 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (3,583, 32.5% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| ACUTE KIDNEY INJURY | 299 |
| NAUSEA | 279 |
| FATIGUE | 248 |
| DYSPNOEA | 238 |
| HYPONATRAEMIA | 230 |
| FALL | 225 |
| VOMITING | 222 |
| DIARRHOEA | 217 |
| PNEUMONIA | 216 |
| ASTHENIA | 200 |
| DIZZINESS | 189 |
| PAIN | 171 |
| PYREXIA | 162 |
| DEHYDRATION | 156 |
| HYPOKALAEMIA | 153 |
| MALAISE | 151 |
| HYPOTENSION | 146 |
| HEADACHE | 144 |
How to read chlorthalidone FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 11,035 voluntary reports linked to chlorthalidone (Thalitone), 2004-2025. Death is listed on 656 (5.9%). Hospitalization appears on 3,583 (32.5%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 32.5% mention hospitalization (3,583 reports).
Read with chlorthalidone
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 11,019 FAERS cases (Δ 16 lighter vs chlorthalidone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 11,087 FAERS cases (Δ 52 heavier vs chlorthalidone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 10,872 FAERS cases (Δ 163 lighter vs chlorthalidone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 11,247 FAERS cases (Δ 212 heavier vs chlorthalidone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 56.2 pp vs chlorthalidone's DEATH-HEAVY): CASELOAD · HOSP-MID.
chlorthalidone stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.