MID-VOLUME · HOSP-HEAVY
amphotericin B Side Effects
amphotericin B (also sold as Ambisome, Fungizone) sits MID-VOLUME #252 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 42.9% mention hospitalization (7,521 reports). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 17,512
- FAERS reports
FDA Adverse Event Reporting System extract for amphotericin B. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.
amphotericin B: 42.9% mention hospitalization (7,521 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #252 of 524 by FAERS report count.
Mid-book FAERS page for amphotericin B (Ambisome) (17,512 reports). Signature HOSP-HEAVY. Dominant age band on file: 45-64. Educational reference only.
Counts from the openFDA FAERS extract (1999–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
PYREXIA leads 972 of 17,512 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (4,641 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (6,407 reports, 36.6%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 516 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 487 |
| SEPSIS | 403 |
| CONDITION AGGRAVATED | 373 |
| RESPIRATORY FAILURE | 370 |
| SEPTIC SHOCK | 336 |
| PNEUMONIA | 323 |
| PYREXIA | 315 |
| DRUG INEFFECTIVE FOR UNAPPROVED INDICATION | 229 |
| RENAL FAILURE | 227 |
| ASPERGILLUS INFECTION | 226 |
| BRONCHOPULMONARY ASPERGILLOSIS | 225 |
| MULTI-ORGAN FAILURE | 219 |
| NEUTROPENIA | 201 |
| RENAL IMPAIRMENT | 189 |
| DISEASE PROGRESSION | 186 |
| FEBRILE NEUTROPENIA | 184 |
| ACUTE KIDNEY INJURY | 177 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (7,521, 42.9% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| PYREXIA | 633 |
| FEBRILE NEUTROPENIA | 430 |
| CONDITION AGGRAVATED | 415 |
| ACUTE KIDNEY INJURY | 406 |
| PNEUMONIA | 389 |
| SEPSIS | 355 |
| RESPIRATORY FAILURE | 314 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 303 |
| SEPTIC SHOCK | 294 |
| ANAEMIA | 272 |
| NEUTROPENIA | 271 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 269 |
| DIARRHOEA | 268 |
| HYPOKALAEMIA | 267 |
| NAUSEA | 261 |
| THROMBOCYTOPENIA | 261 |
| HYPOTENSION | 256 |
| RENAL FAILURE | 245 |
How to read amphotericin B FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 17,512 voluntary reports linked to amphotericin B (Ambisome, Fungizone), 1999-2025. Death is listed on 6,407 (36.6%). Hospitalization appears on 7,521 (42.9%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 42.9% mention hospitalization (7,521 reports).
Read with amphotericin B
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 17,378 FAERS cases (Δ 134 lighter vs amphotericin B); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 17,680 FAERS cases (Δ 168 heavier vs amphotericin B); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 17,328 FAERS cases (Δ 184 lighter vs amphotericin B); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 17,740 FAERS cases (Δ 228 heavier vs amphotericin B); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 0.0% death-mentioned reports (Δ 36.6 pp vs amphotericin B's DEATH-HEAVY): MEGA-CASE · HOSP-LIGHT.
amphotericin B stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.