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Two medicines, side by side

Sulfur vs salicylic acid

Sulfur and salicylic acid are both labeled for acne.

Check it at the source: the sulfur FDA label on DailyMed (effective November 15, 2023); the salicylic acid FDA label on DailyMed (effective October 22, 2024).

Highlights of the sulfur record

Sulfur (Bensulfoid) · label of November 15, 2023

Used for

From the label: indications

Skin Rash Worsened By Heat And Water*

On the market

Earliest approval on file
September 17, 1940
Generic labelers
none listed
Pharmacy cost
Not in the survey

Supply and safety

Shortage
No current entry
Recalls
0

Highlights of the salicylic acid record

Salicylic acid · label of October 22, 2024

Used for

From the label: indications

For the treatment of acne.

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.102 per patch

Supply and safety

Shortage
No current entry
Recalls
1

Source: FDA drug labels via openFDA (Sulfur label of November 15, 2023, Salicylic acid label of October 22, 2024); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do sulfur and salicylic acid differ on the record?

SulfurSalicylic acid
Labeled forAcneAcne, Pain, Psoriasis
Pharmacologic classn/an/a
How it works (label)n/an/a
Half-life (label)n/an/a
Earliest approval on file (Drugs@FDA)September 17, 1940n/a
First generic approvednonenone
Generic labelers (NDC)none listednone listed
Pharmacy cost (NADAC, each one's most listed form; strengths differ)n/a$0.102 per patch (Callus removers patch)
12-month price changen/a+10%
Boxed warningNoNo
Shortage nowNo current entryNo current entry
Recalls recorded01
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)8,40552,581
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to sulfur
every medicine labeled for the same conditions