ofloxacin vs theophylline
Side-by-side comparison of ofloxacin and theophylline. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
major Known Drug Interaction
70% increase Ciprofloxacin Similar to cimetidine. albuterol, systemic and inhaled mebendazole amoxicillin medroxyprogesterone ampicillin, with or without sulbactam methylprednisolone atenolol metronidazole azithromycin metoprolol caffeine, dietary ingestion nadolol cefaclor nifedipine co-trimoxazole (trimethoprim and sulfamethoxazole) nizatidine diltiazem norfloxacin dirithromycin ofloxacin enflurane omeprazole famotidine prednisone, prednisolone felodipine ranitidine finasteride rifabutin hydrocortisone roxithromycin isoflurane Sorbitol (purgative doses do not inhibit theophylline...
Recommendation: Your doctor may need to lower your theophylline dose while you take this antibiotic. Seek medical help immediately if you feel very restless or have a seizure.
Floxin, Ocuflox
Theo-24, Elixophyllin
Ofloxacin ear drops are an antibiotic medicine. They fight bacteria to treat ear infections.
Theophylline is a medicine that helps you breathe easier. It treats the symptoms of asthma and other lung problems.
This medicine treats ear infections caused by certain bacteria. It can treat outer ear infections in adults and kids over 6 months old. It also treats middle ear infections with a hole in the eardrum in people 12 and older, and middle ear infections with ear tubes in kids 1 year and older.
Theophylline treats the symptoms of long-term asthma and other lung diseases. These include emphysema and chronic bronchitis, which make it hard to breathe. This medicine helps to open up your airways so you can breathe easier.
Ofloxacin belongs to a class of drugs called fluoroquinolone antibiotics. It works by stopping the growth of bacteria. This helps to clear up the infection in your ear.
Theophylline is a bronchodilator. It works by relaxing the muscles in your airways. This allows more air to flow in and out of your lungs.
- • Application site reaction
- • Itching
- • Taste changes
- • Nausea
- • Vomiting
- • Headache
- • Trouble sleeping (insomnia)
- Eye pain 345
- Headache 284
- Pain 278
- Tiredness 257
- Feeling sick to your stomach 251
- Difficulty breathing 2,273
- Asthma 1,942
- Pneumonia 1,317
- Wheezing 1,306
- Vomiting 1,101
You should not take this medicine if you are allergic to ofloxacin or other quinolone antibiotics, or any of the ingredients in the drops.
If your theophylline levels get too high in your blood, it can cause serious side effects. These include severe vomiting, irregular heartbeats, and seizures. These can be life-threatening.
Tell your doctor if you are pregnant or breastfeeding. It is not known if ofloxacin ear drops will harm an unborn baby or pass into breast milk.
It is not known if theophylline can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if theophylline passes into breast milk, so talk to your doctor if you are breastfeeding.
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How to Read This ofloxacin vs theophylline Comparison
ofloxacin is classified in the Fluoroquinolone Antibiotic drug class, while theophylline sits within the Methylxanthine Bronchodilator class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, ofloxacin has 1,415 submissions while theophylline has 7,939. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known major interaction flagged in FDA labeling, attributed to ofloxacin can stop your liver from breaking down theophylline as fast as it should. this can lead to a significant increase in the amount of theophylline in your system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between ofloxacin and theophylline - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.