metoclopramide vs tetracycline

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Side-by-side comparison of metoclopramide and tetracycline. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

digoxin) by metoclopramide, whereas the rate and/or extent of absorption of drugs from the small bowel may be increased (e.g., acetaminophen, tetracycline, levodopa, ethanol, cyclosporine).

Drug Class
metoclopramide Prokinetic / Antiemetic
tetracycline Tetracycline Antibiotic
Type
metoclopramide Prescription
tetracycline Prescription
Summary
metoclopramide

Metoclopramide is a drug that helps with stomach problems. It can help food move faster through your stomach and reduce nausea.

tetracycline

Tetracycline is an antibiotic medicine. It fights bacteria in your body to treat different types of infections.

What It Treats
metoclopramide

This medicine treats heartburn caused by acid reflux when other treatments don't work. It also helps with symptoms of slow stomach emptying in people with diabetes, like nausea, vomiting, and feeling full. This medicine is for adults and should not be used for more than 12 weeks.

tetracycline

Tetracycline treats many kinds of infections caused by bacteria. This includes infections of the lungs, skin, urinary tract, and some sexually transmitted infections. It can also treat acne and other less common infections like brucellosis, tularemia, or cholera. Your doctor will decide if tetracycline is right for your infection.

How It Works
metoclopramide

Metoclopramide helps your stomach muscles move faster. This helps food empty from your stomach more quickly. It also blocks a chemical in your brain that causes nausea.

tetracycline

Tetracycline works by stopping bacteria from growing and multiplying. It prevents the bacteria from making proteins they need to survive. This helps your body's immune system fight off the infection.

Common Side Effects
metoclopramide
  • Restlessness
  • Drowsiness
  • Fatigue
  • Feeling tired
tetracycline
  • Nausea
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Stomach upset
FAERS Reports
metoclopramide
  • Tardive Dyskinesia 13,205
  • Extrapyramidal Disorder 11,628
  • Nervous System Disorder 7,175
  • Dystonia 6,661
  • Pain 4,666
tetracycline
  • Drug Hypersensitivity 151
  • Hypersensitivity 123
  • Pneumonia 103
  • Pain In Extremity 93
  • Arthralgia 90
Serious Warnings
metoclopramide

Metoclopramide can cause a serious movement disorder called tardive dyskinesia. This may not go away even after you stop taking the medicine. The risk of tardive dyskinesia increases with long-term use and high doses. Call your doctor right away if you have uncontrolled muscle movements.

tetracycline

Tetracycline can cause permanent tooth discoloration if used during tooth development. This means it should not be used in pregnant women or children under 8 years old. Tetracycline can also make your skin more sensitive to the sun, so avoid prolonged sun exposure.

Pregnancy
metoclopramide

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby. Talk to your doctor about the risks and benefits of taking this medicine while breastfeeding.

tetracycline

Tetracycline can harm an unborn baby. You should not take tetracycline if you are pregnant. Tetracycline can also pass into breast milk and may affect the baby. Talk to your doctor about safe alternatives if you are breastfeeding.

Also Compare, Nearby Drugs

How to Read This metoclopramide vs tetracycline Comparison

metoclopramide is classified in the Prokinetic / Antiemetic drug class, while tetracycline sits within the Tetracycline Antibiotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, metoclopramide has 43,335 submissions while tetracycline has 560. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to metoclopramide makes the stomach empty faster, which can cause the body to absorb more of the tetracycline antibiotic than usual.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for metoclopramide or tetracycline.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.