lurasidone vs verapamil
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Side-by-side comparison of lurasidone and verapamil. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Examples: Diltiazem, atazanavir, erythromycin, fluconazole, verapamil Strong CYP3A4 Inducers Clinical Impact: Concomitant use of lurasidone hydrochloride with strong CYP3A4 inducers decreased the exposure of lurasidone compared to the use of lurasidone hydrochloride alone [see Clinical Pharmacology ( 12.3 )].
Latuda
Calan, Verelan
Lurasidone (Latuda) is a medicine used to treat schizophrenia and bipolar depression. It helps to balance chemicals in the brain.
Verapamil is a drug that helps to lower blood pressure and treat chest pain (angina) and irregular heartbeats (arrhythmias). It works by relaxing blood vessels and slowing down the heart rate.
Lurasidone is used to treat schizophrenia in adults and teens ages 13-17. It also treats the depressive phase of bipolar disorder in adults and children ages 10-17. In adults, it can be used alone or with lithium or valproate for bipolar depression.
Verapamil is used to treat chest pain called angina. This includes angina that happens when you are resting or during normal activity. It is also used to control your heart rate if you have a fast or irregular heartbeat, such as atrial fibrillation or atrial flutter. Verapamil also treats high blood pressure.
Lurasidone is an atypical antipsychotic. It works by affecting certain chemicals in the brain, such as dopamine and serotonin. This helps to improve mood, thinking, and behavior.
Verapamil belongs to a class of drugs called calcium channel blockers. It works by blocking calcium from entering heart and blood vessel cells. This relaxes and widens blood vessels, which lowers blood pressure and makes it easier for the heart to pump.
- • Feeling sleepy
- • Feeling restless and needing to move
- • Nausea
- • Weight gain
- • Trouble sleeping
- • Constipation
- • Shortness of breath
- • Dizziness
- • Slow heart rate (less than 50 beats per minute)
- • Nausea
- Anxiety 1,223
- Feeling Abnormal 1,166
- Depression 1,120
- Weight Increased 1,077
- Somnolence 1,066
- Dyspnoea 356
- Nausea 341
- Drug Interaction 316
- Dizziness 286
- Hypotension 280
This medicine has two important warnings: * **Increased risk of death in elderly people with dementia:** If you are an older adult with dementia-related psychosis, this medicine may increase your chance of death. Lurasidone is not approved for this condition. * **Increased risk of suicidal thoughts and behaviors:** Antidepressants may increase the risk of suicidal thoughts and behaviors in children, teens, and young adults. Your doctor will need to watch you closely for worsening mood or suicidal thoughts.
You should not take this medicine if you have severe heart problems, very low blood pressure, or certain types of irregular heartbeats without a pacemaker. Talk to your doctor if you have any of these conditions.
Tell your doctor if you are pregnant or plan to become pregnant. Babies born to mothers who take this medicine in the last 3 months of pregnancy may have withdrawal symptoms or other problems after birth. Talk to your doctor about the risks and benefits of taking lurasidone during pregnancy.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not known if verapamil will harm your unborn baby. Verapamil can pass into breast milk, so talk to your doctor about the best way to feed your baby if you take this medicine.
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How to Read This lurasidone vs verapamil Comparison
lurasidone is classified in the Atypical Antipsychotic drug class, while verapamil sits within the Calcium Channel Blocker class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, lurasidone has 5,652 submissions while verapamil has 1,579. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to verapamil causes your body to process lurasidone more quickly, leading to lower levels of the drug in your system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for lurasidone or verapamil.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.