lovastatin vs posaconazole
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Side-by-side comparison of lovastatin and posaconazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
Strong inhibitors of CYP3A4 (e.g., itraconazole, ketoconazole, posaconazole, voriconazole, clarithromycin, telithromycin, HIV protease inhibitors, boceprevir, telaprevir, nefazodone, erythromycin, and cobicistat-containing products), and grapefruit juice increase the risk of myopathy by reducing the elimination of lovastatin (see CONTRAINDICATIONS , WARNINGS , Myopathy/Rhabdomyolysis , and CLINICAL PHARMACOLOGY , Pharmacokinetics ).
Mevacor, Altoprev
Noxafil
Lovastatin is a medicine that helps lower cholesterol levels in your blood. It belongs to a class of drugs called statins.
Posaconazole is an antifungal medicine. It helps prevent certain fungal infections in people with weakened immune systems.
Lovastatin is used to lower cholesterol and reduce the risk of heart problems. It can help prevent heart attacks, unstable angina (chest pain), and the need for procedures to open blocked arteries. It's also used to slow down the hardening of arteries in people who already have heart disease. Lovastatin can also be used in children 10-17 years of age with high cholesterol due to genetic causes.
Posaconazole prevents Aspergillus and Candida infections. You may need this medicine if you have a high risk of getting these infections. This often includes people who had a stem cell transplant or have certain blood cancers and are on chemotherapy.
Lovastatin works by blocking a substance your body needs to make cholesterol. This helps to lower the amount of cholesterol in your blood. Lowering cholesterol helps to prevent heart disease and stroke.
Posaconazole belongs to a class of drugs called azole antifungals. It works by stopping the growth of fungi. This helps your body fight off the infection.
- • Abdominal pain
- • Constipation
- • Diarrhea
- • Gas
- • Nausea
- • Diarrhea
- • Nausea
- • Fever
- • Vomiting
- • Headache
- Fatigue 1,518
- Nausea 1,396
- Diarrhoea 1,251
- Dyspnoea 1,209
- Dizziness 1,147
- Febrile Neutropenia 1,017
- Drug Interaction 930
- Death 928
- Pyrexia 850
- Neutropenia 705
Lovastatin can cause muscle problems, including muscle breakdown (rhabdomyolysis), which can lead to kidney damage. The risk is higher if you take certain other medicines with lovastatin. You should not take lovastatin if you have liver problems or are pregnant or breastfeeding.
Posaconazole can interact with many other medicines. It can cause heart rhythm problems (QT prolongation). It can also cause liver problems. Tell your doctor about all the medicines you take.
You should not take lovastatin if you are pregnant or breastfeeding. It can harm your unborn baby. If you are a woman who could become pregnant, use effective birth control while taking lovastatin.
Posaconazole may harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if posaconazole passes into breast milk, so talk to your doctor if you are breastfeeding.
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How to Read This lovastatin vs posaconazole Comparison
lovastatin is classified in the HMG-CoA Reductase Inhibitor (Statin) drug class, while posaconazole sits within the Azole Antifungal class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, lovastatin has 6,521 submissions while posaconazole has 4,430. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to posaconazole stops the body from removing lovastatin properly, which can cause the drug to reach dangerous levels. this buildup increases the risk of a serious muscle-wasting condition.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for lovastatin or posaconazole.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.