lisdexamfetamine vs simvastatin

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Side-by-side comparison of lisdexamfetamine and simvastatin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

From a pharmacokinetic perspective, no dose adjustment for drugs that are substrates of CYP1A2 (e.g., theophylline, duloxetine, melatonin), CYP2D6 (e.g., atomoxetine, desipramine, venlafaxine), CYP2C19 (e.g., omeprazole, lansoprazole, clobazam), and CYP3A4 (e.g., midazolam, pimozide, simvastatin) is necessary when VYVANSE is co-administered [see Clinical Pharmacology (12.3) ] .

Drug Class
lisdexamfetamine CNS Stimulant
simvastatin HMG-CoA Reductase Inhibitor (Statin)
Type
lisdexamfetamine Prescription
simvastatin Prescription
Summary
lisdexamfetamine

Lisdexamfetamine (Vyvanse) is a stimulant medicine. It can help improve focus and reduce impulsive behavior.

simvastatin

No summary available.

What It Treats
lisdexamfetamine

This medicine treats Attention Deficit Hyperactivity Disorder (ADHD) in adults and kids 6 years and older. It also treats moderate to severe binge eating disorder (BED) in adults. This medicine is not for weight loss.

simvastatin

Information not available.

How It Works
lisdexamfetamine

Lisdexamfetamine affects chemicals in your brain. These chemicals help control hyperactivity and impulses. It can also help reduce binge eating.

simvastatin

Information not available.

Common Side Effects
lisdexamfetamine
  • Anorexia
  • Anxiety
  • Decreased appetite
  • Weight loss
  • Diarrhea
simvastatin
  • Headache
  • Upper respiratory tract infection
  • Muscle pain
  • Diarrhea
FAERS Reports
lisdexamfetamine
  • Intentional Overdose 1,068
  • Intentional Self-Injury 1,009
  • Product Availability Issue 487
  • Fatigue 402
  • Headache 377
simvastatin
  • Fatigue 13,574
  • Nausea 12,945
  • Dyspnoea 12,431
  • Diarrhoea 11,813
  • Dizziness 10,971
Serious Warnings
lisdexamfetamine

This medicine has a high risk for abuse, misuse, and addiction. Misusing it can lead to overdose and death. Your doctor will check your risk before and during treatment. Store this medicine safely and do not share it with anyone.

simvastatin

No specific warnings noted.

Pregnancy
lisdexamfetamine

This medicine may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Breastfeeding is not recommended while taking this medicine.

simvastatin

No pregnancy information available.

Also Compare, Nearby Drugs

How to Read This lisdexamfetamine vs simvastatin Comparison

lisdexamfetamine is classified in the CNS Stimulant drug class, while simvastatin sits within the HMG-CoA Reductase Inhibitor (Statin) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, lisdexamfetamine has 3,343 submissions while simvastatin has 61,734. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to lisdexamfetamine does not interfere with the way your body processes this cholesterol medicine. both drugs can work normally without affecting each other's levels.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for lisdexamfetamine or simvastatin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.