levofloxacin vs sucralfate
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Side-by-side comparison of levofloxacin and sucralfate. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Monitor prothrombin time, INR and watch for bleeding (7.2) Antidiabetic agents Carefully monitor blood glucose (5.13, 7.3) 7.1 Chelation Agents: Antacids, Sucralfate, Metal Cations, Multivitamins While the chelation by divalent cations is less marked than with other fluoroquinolones, concurrent administration of levofloxacin tablets with antacids containing magnesium, or aluminum, as well as sucralfate, metal cations such as iron, and multivitamin preparations with zinc may interfere with the gastrointestinal absorption of levofloxacin, resulting in systemic levels considerably lower than...
Levaquin
Carafate
Levofloxacin is an antibiotic that fights bacteria in your body. It is used to treat different types of infections.
Sucralfate is a medicine that helps heal and protect ulcers in your small intestine. It creates a coating over the ulcer to shield it from stomach acid.
Levofloxacin treats infections like pneumonia, skin infections, prostate infections, and urinary tract infections. It can also treat anthrax after exposure and plague. This medicine should only be used for certain infections when other options won't work.
Sucralfate is used to treat active duodenal ulcers, which are sores in the first part of your small intestine. It can help heal these ulcers over a period of 4 to 8 weeks. Sucralfate can also be used as maintenance therapy at a lower dose to prevent ulcers from coming back after they have healed.
Levofloxacin belongs to a class of drugs called fluoroquinolones. It works by stopping bacteria from multiplying. This helps your body fight off the infection.
Sucralfate works by forming a protective layer over the ulcer. This coating acts like a bandage, shielding the ulcer from stomach acid and enzymes. This protection helps the ulcer heal.
- • Nausea
- • Headache
- • Diarrhea
- • Trouble sleeping
- • Constipation
- • Constipation (2%)
- Dyspnoea 2,950
- Pneumonia 2,863
- Nausea 2,790
- Pyrexia 2,723
- Fatigue 2,659
- Nausea 2,262
- Fatigue 1,733
- Diarrhoea 1,700
- Pain 1,481
- Headache 1,381
This drug has serious warnings. Levofloxacin can cause tendon problems, nerve damage, and central nervous system effects. It can also make muscle weakness worse if you have myasthenia gravis. If you have any of these side effects, stop taking the medicine and call your doctor right away. Only use this medicine if you have no other treatment options for uncomplicated urinary tract infections, bronchitis, or sinusitis.
Inadvertent injection of sucralfate has led to fatal complications, including blood clots in the lungs and brain. Sucralfate is not intended for intravenous administration.
Tell your doctor if you are pregnant or plan to become pregnant. Levofloxacin should only be used during pregnancy if the benefit outweighs the risk to the baby. It may pass into breast milk, so talk to your doctor about breastfeeding.
It is not known if sucralfate can harm an unborn baby. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
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How to Read This levofloxacin vs sucralfate Comparison
levofloxacin is classified in the Fluoroquinolone Antibiotic drug class, while sucralfate sits within the Mucosal Protective Agent class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, levofloxacin has 13,985 submissions while sucralfate has 8,557. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to sucralfate attaches to the medicine in your stomach and prevents it from being absorbed into your body. this means the antibiotic might not work well enough to kill the bacteria.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for levofloxacin or sucralfate.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.