haloperidol vs vasopressin
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Side-by-side comparison of haloperidol and vasopressin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
7.4 Drugs Suspected of Causing SIADH Use with drugs suspected of causing SIADH (e.g., SSRIs, tricyclic antidepressants, haloperidol, chlorpropamide, enalapril, methyldopa, pentamidine, vincristine, cyclophosphamide, ifosfamide, felbamate) may increase the pressor effect in addition to the antidiuretic effect of Vasopressin injection.
Haldol
Vasostrict
Haloperidol is a medicine used to treat mental disorders. It can help reduce symptoms like hallucinations and confused thinking.
Vasopressin injection helps raise blood pressure in adults with shock. It is used when fluids and other medicines don't work well enough.
Haloperidol is used to manage symptoms of psychotic disorders. It can also control tics and vocal sounds in people with Tourette's Disorder. In children, it can treat severe behavior problems like being combative or overly excitable when other treatments haven't worked. It can also be used short-term for hyperactive children with impulsivity and difficulty paying attention.
Vasopressin injection is used to increase blood pressure. It is for adults who have vasodilatory shock. This is when blood vessels relax too much, causing low blood pressure. It is used when fluids and other medicines called catecholamines are not enough to raise blood pressure.
Haloperidol works by changing the effect of certain natural chemicals in the brain. These chemicals, called neurotransmitters, affect mood and behavior. By blocking dopamine, haloperidol helps to reduce psychotic symptoms.
Vasopressin is a hormone that makes blood vessels get tighter. This helps to increase blood pressure. It can also affect how your kidneys handle water.
- • Muscle stiffness
- • Shaking
- • Slow movement
- • Restlessness
- • Changes in heart rhythm
- • Decreased heart output
- • Slow heart rate
- • Fast or irregular heart rate
- • Low sodium levels in the blood
- • Reduced blood flow to the heart
- Drug Interaction 1,663
- Neuroleptic Malignant Syndrome 1,577
- Weight Increased 1,216
- Extrapyramidal Disorder 1,201
- Toxicity To Various Agents 999
- Hypotension 486
- Cardiogenic Shock 389
- Sepsis 380
- Multiple Organ Dysfunction Syndrome 375
- Condition Aggravated 359
Haloperidol may increase the risk of death in elderly patients with dementia-related psychosis. Haloperidol is not approved to treat dementia-related psychosis.
Vasopressin can worsen heart function. It can also cause a type of diabetes where you pee a lot. Your doctor will check your electrolytes and urine after you stop taking it.
Tell your doctor if you are pregnant or plan to become pregnant. Haloperidol may cause side effects in newborns if taken during pregnancy. Talk to your doctor about the risks and benefits of taking haloperidol while breastfeeding.
Vasopressin may cause the uterus to contract, which could be a problem during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if vasopressin passes into breast milk.
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How to Read This haloperidol vs vasopressin Comparison
haloperidol is classified in the Typical Antipsychotic drug class, while vasopressin sits within the Vasopressin Receptor Agonist class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, haloperidol has 6,656 submissions while vasopressin has 1,989. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to haloperidol may cause the body to keep too much water, which makes the effects of vasopressin stronger. this can increase blood pressure and water buildup in the body.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for haloperidol or vasopressin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.