furosemide vs sucralfate
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Side-by-side comparison of furosemide and sucralfate. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Simultaneous administration of sucralfate and furosemide tablets may reduce the natriuretic and antihypertensive effects of furosemide. The intake of furosemide and sucralfate should be separated by at least two hours.
Lasix
Carafate
Furosemide is a water pill (diuretic). It helps your body get rid of extra water and salt.
Sucralfate is a medicine that helps heal and protect ulcers in your small intestine. It creates a coating over the ulcer to shield it from stomach acid.
This medicine treats swelling (edema) from heart failure, liver problems, or kidney disease. It can also treat high blood pressure. Furosemide is helpful when you need a stronger diuretic.
Sucralfate is used to treat active duodenal ulcers, which are sores in the first part of your small intestine. It can help heal these ulcers over a period of 4 to 8 weeks. Sucralfate can also be used as maintenance therapy at a lower dose to prevent ulcers from coming back after they have healed.
Furosemide works in your kidneys. It helps your kidneys remove more salt and water from your blood. This lowers the amount of fluid in your body and lowers blood pressure.
Sucralfate works by forming a protective layer over the ulcer. This coating acts like a bandage, shielding the ulcer from stomach acid and enzymes. This protection helps the ulcer heal.
- • Dizziness
- • Headache
- • Blurred vision
- • Nausea
- • Vomiting
- • Constipation (2%)
- Dyspnoea 29,104
- Fatigue 20,393
- Diarrhoea 19,937
- Nausea 18,692
- Acute Kidney Injury 18,530
- Nausea 2,262
- Fatigue 1,733
- Diarrhoea 1,700
- Pain 1,481
- Headache 1,381
Furosemide can cause you to lose too much fluid and electrolytes. This can lead to dehydration, low blood pressure, and kidney problems. Your doctor should check your blood regularly while you are taking this medicine.
Inadvertent injection of sucralfate has led to fatal complications, including blood clots in the lungs and brain. Sucralfate is not intended for intravenous administration.
Tell your doctor if you are pregnant or plan to become pregnant. Furosemide may not be safe during pregnancy. Talk to your doctor about the risks and benefits of taking this medicine while breastfeeding.
It is not known if sucralfate can harm an unborn baby. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
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How to Read This furosemide vs sucralfate Comparison
furosemide is classified in the Loop Diuretic drug class, while sucralfate sits within the Mucosal Protective Agent class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, furosemide has 106,656 submissions while sucralfate has 8,557. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to sucralfate can prevent the body from absorbing furosemide correctly when they are taken at the same time. this makes the furosemide less effective at lowering blood pressure and removing extra fluid.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for furosemide or sucralfate.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.