folic acid vs phenytoin
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Side-by-side comparison of folic acid and phenytoin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Table 1: Drugs That Affect Phenytoin Concentrations Interacting Agent Examples Drugs that may increase phenytoin serum levels Antiepileptic drugs Ethosuximide, felbamate, oxcarbazepine, methsuximide, topiramate Azoles Fluconazole, ketoconazole, itraconazole, miconazole, voriconazole Antineoplastic agents Capecitabine, fluorouracil Antidepressants Fluoxetine, fluvoxamine, sertraline Gastric acid reducing agents H 2 antagonists (cimetidine), omeprazole Sulfonamides Sulfamethizole, sulfaphenazole, sulfadiazine, sulfamethoxazole trimethoprim Other Acute alcohol intake, amiodarone,...
Folvite
Dilantin
Integra FTM is a medicine that helps treat iron and folate deficiencies. It is also used during pregnancy to prevent and treat iron deficiency and provide folic acid.
Phenytoin injection is used to treat certain types of seizures. It can also prevent seizures during or after neurosurgery.
Integra FTM treats iron deficiency anemia and folate deficiency anemia. It is also used during pregnancy to prevent and treat iron deficiency. This medicine also provides a maintenance dosage of folic acid during pregnancy.
This medicine treats generalized tonic-clonic status epilepticus, a type of prolonged seizure. It also helps prevent and treat seizures that may happen during or after brain surgery. Sometimes, it can be used for a short time instead of the oral form of phenytoin when you cannot take the medicine by mouth.
Integra FTM contains two types of iron that your body can use. These iron types help to increase the amount of iron in your blood. Folic acid is a B vitamin that helps your body make new blood cells.
Phenytoin works by slowing down the signals in the brain that cause seizures. It stabilizes nerve cell membranes, reducing excessive electrical activity. This helps to prevent seizures from starting or spreading.
- • Upset stomach
- • Nausea
- • Diarrhea
- • Constipation
- • Heartburn
No common side effects listed.
- Fatigue 23,332
- Pain 23,054
- Arthralgia 19,495
- Rheumatoid Arthritis 17,528
- Nausea 15,633
- Drug Interaction 1,547
- Seizure 1,382
- Toxicity To Various Agents 1,353
- Convulsion 1,262
- Status Epilepticus 791
Accidental overdose of iron-containing products is a leading cause of fatal poisoning in young children. Keep this medicine away from children. If someone overdoses, call a doctor or poison control center right away. Folic acid alone is not the right treatment for pernicious anemia or other megaloblastic anemias where Vitamin B12 is lacking.
This medicine can cause serious heart problems if given too quickly. The injection rate should not be faster than 50 mg per minute for adults, and 1 to 3 mg/kg/min (or 50 mg per minute, whichever is slower) for children. Your heart will be monitored closely during and after the injection.
Integra FTM can be used during pregnancy to prevent and treat iron deficiency and to provide folic acid. Talk to your doctor before taking this medicine if you are pregnant or breastfeeding.
Taking phenytoin during pregnancy may increase the risk of birth defects. If you are pregnant or plan to become pregnant, talk to your doctor about the risks and benefits of this medicine.
How to Read This folic acid vs phenytoin Comparison
folic acid is classified in the B Vitamin (Folate) Supplement drug class, while phenytoin sits within the Anticonvulsant (Hydantoin) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, folic acid has 99,042 submissions while phenytoin has 6,335. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to taking these two together can cause the levels of both drugs in your blood to drop, making them both less effective.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for folic acid or phenytoin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.