erythromycin vs felodipine

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Side-by-side comparison of erythromycin and felodipine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Co-administration of CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, erythromycin, grapefruit juice, cimetidine) with felodipine may lead to several-fold increases in the plasma levels of felodipine, either due to an increase in bioavailability or due to a decrease in metabolism. Erythromycin Co-administration of felodipine with erythromycin resulted in approximately 2.5-fold increase in the AUC and C max , and about 2-fold prolongation in the half-life of felodipine.

Drug Class
erythromycin Macrolide Antibiotic
felodipine Calcium Channel Blocker
Type
erythromycin Prescription
felodipine Prescription
Summary
erythromycin

Erythromycin Topical Solution is a medicine that you put on your skin to treat acne. It contains an antibiotic to help clear up your skin.

felodipine

Felodipine is a drug that lowers your blood pressure. Lowering blood pressure reduces the risk of strokes and heart attacks.

What It Treats
erythromycin

Erythromycin Topical Solution treats acne vulgaris. This medicine helps to reduce acne on your face, neck, shoulders, chest, and back. It works by fighting the bacteria that cause acne.

felodipine

Felodipine treats high blood pressure (hypertension). Lowering your blood pressure helps prevent strokes and heart attacks. It's important to also manage other risk factors like cholesterol, diabetes, and smoking. You may need more than one medicine to control your blood pressure.

How It Works
erythromycin

Erythromycin is a macrolide antibiotic. It works by stopping the growth of bacteria. This helps to reduce inflammation and clear up acne.

felodipine

Felodipine is a calcium channel blocker. It works by relaxing and widening your blood vessels. This makes it easier for blood to flow, which lowers blood pressure.

Common Side Effects
erythromycin
  • Peeling
  • Dryness
  • Itching
  • Redness
  • Oily skin
felodipine
  • Swelling in your ankles or feet
  • Headache
  • Flushing (redness of face)
  • Feeling tired
FAERS Reports
erythromycin
  • Drug Hypersensitivity 4,088
  • Nausea 1,271
  • Vomiting 1,121
  • Diarrhoea 1,069
  • Dyspnoea 1,023
felodipine
  • Fatigue 1,051
  • Dyspnoea 952
  • Dizziness 946
  • Diarrhoea 846
  • Nausea 846
Serious Warnings
erythromycin

You should not use this medicine if you are allergic to any of its ingredients.

felodipine

If you take certain medicines like ketoconazole, itraconazole, or erythromycin, talk to your doctor. These drugs can greatly increase the amount of felodipine in your blood, leading to unwanted effects. Also, if you take anticonvulsants like phenytoin, carbamazepine, or phenobarbital, felodipine may not work as well.

Pregnancy
erythromycin

It is not known if erythromycin topical solution can harm an unborn baby. Talk to your doctor if you are pregnant or breastfeeding.

felodipine

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if felodipine will harm your unborn baby. Talk to your doctor about breastfeeding while taking felodipine.

Also Compare, Nearby Drugs

How to Read This erythromycin vs felodipine Comparison

erythromycin is classified in the Macrolide Antibiotic drug class, while felodipine sits within the Calcium Channel Blocker class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, erythromycin has 8,572 submissions while felodipine has 4,641. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to erythromycin slows down how fast your body gets rid of felodipine. this leads to much higher amounts of felodipine in your system than usual.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for erythromycin or felodipine.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.