dutasteride/tamsulosin vs nifedipine

According to this portal's Publishing Organization, this page was last reviewed in August 2026 against our methodology. Figures and extracts on this site, including tables above 1,000 rows when the corpus is that large, are the publisher's responsibility.

Side-by-side comparison of dutasteride/tamsulosin and nifedipine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

7.3 Nifedipine, Atenolol, Enalapril Tamsulosin Dosage adjustments are not necessary when tamsulosin is administered concomitantly with nifedipine, atenolol, or enalapril [see Clinical Pharmacology ( 12.3 ) ] .

Drug Class
dutasteride/tamsulosin 5-ARI / Alpha-Blocker Combination
nifedipine Calcium Channel Blocker
Type
dutasteride/tamsulosin Prescription
nifedipine Prescription
Summary
dutasteride/tamsulosin

This medicine combines two drugs to treat enlarged prostate in men. It helps improve urine flow and reduce symptoms.

nifedipine

Nifedipine is a calcium channel blocker. It helps to relax blood vessels, which can lower blood pressure and reduce chest pain.

What It Treats
dutasteride/tamsulosin

This medicine treats benign prostatic hyperplasia (BPH), also known as enlarged prostate, in men. It helps to relieve symptoms like frequent urination, difficulty starting urination, and weak urine stream. This medicine is not approved to prevent prostate cancer.

nifedipine

This medicine treats chest pain (angina) caused by tight blood vessels. It also treats high blood pressure. Lowering blood pressure reduces the risk of strokes and heart attacks.

How It Works
dutasteride/tamsulosin

This medicine contains two drugs that work in different ways. Dutasteride lowers a hormone called DHT that causes the prostate to grow. Tamsulosin relaxes the muscles in the prostate and bladder, making it easier to urinate.

nifedipine

Nifedipine blocks calcium from entering heart and blood vessel cells. This relaxes and widens blood vessels. As a result, the heart doesn't have to work as hard, and blood pressure goes down.

Common Side Effects
dutasteride/tamsulosin
  • Problems with ejaculation
  • Impotence (trouble getting or keeping an erection)
  • Decreased sex drive
  • Dizziness
  • Breast enlargement or tenderness
nifedipine
  • Swelling, especially in the legs or ankles
  • Headache
  • Fatigue
  • Dizziness
  • Constipation
FAERS Reports
dutasteride/tamsulosin
  • Shortness of breath 1,233
  • Tiredness 1,142
  • Feeling lightheaded or unsteady 986
  • Weakness 933
  • Loose stools 897
nifedipine
  • Dyspnoea 2,429
  • Fatigue 2,304
  • Diarrhoea 2,264
  • Nausea 2,220
  • Headache 1,997
Serious Warnings
dutasteride/tamsulosin

This medicine can cause dizziness, lightheadedness, and fainting, especially when you stand up. Be careful to avoid falls or injuries. Do not take this medicine with other alpha-blockers, as it can lower your blood pressure too much. This medicine can affect your PSA levels, which are used to screen for prostate cancer, so tell your doctor you are taking this medicine. Pregnant women should not handle this medicine, as it can harm a male fetus.

nifedipine

In rare cases, nifedipine can cause serious gastrointestinal problems, including obstruction. If you experience severe abdominal pain, vomiting, or inability to pass stool, seek immediate medical attention.

Pregnancy
dutasteride/tamsulosin

This medicine is not for women. It can harm a male fetus if a pregnant woman is exposed to it. Pregnant women should not handle this medicine.

nifedipine

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if nifedipine will harm your unborn baby. Talk to your doctor about the risks and benefits of taking this medicine while pregnant or breastfeeding.

Also Compare, Nearby Drugs

How to Read This dutasteride/tamsulosin vs nifedipine Comparison

dutasteride/tamsulosin is classified in the 5-ARI / Alpha-Blocker Combination drug class, while nifedipine sits within the Calcium Channel Blocker class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, dutasteride/tamsulosin has 5,191 submissions while nifedipine has 11,214. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to these two drugs do not interfere with each other, so the amount of medicine in your body stays the same.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for dutasteride/tamsulosin or nifedipine.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.