dronabinol vs warfarin
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Side-by-side comparison of dronabinol and warfarin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
(7.3) Highly protein-bound drugs: Potential for displacement of other drugs from plasma proteins; monitor for adverse reactions to concomitant highly protein-bound drugs and narrow therapeutic index drugs (e.g., warfarin, cyclosporine, amphotericin B) when initiating or increasing the dosage of dronabinol capsules. Although this displacement has not been confirmed in vivo , monitor patients for increased adverse reactions to narrow therapeutic index drugs that are highly protein-bound (e.g., warfarin, cyclosporine, amphotericin B) when initiating treatment or increasing the dosage of...
Marinol
Coumadin, Jantoven
Dronabinol capsules contain a synthetic form of THC, the active ingredient in marijuana. It is used to treat loss of appetite in AIDS patients and nausea/vomiting from chemotherapy.
Warfarin is a medicine that helps prevent blood clots. It is used to treat and prevent dangerous clots from forming in your body.
Dronabinol is used to treat loss of appetite and weight loss in adults with Acquired Immune Deficiency Syndrome (AIDS). It also helps with nausea and vomiting caused by cancer chemotherapy when other treatments don't work well. Dronabinol can help you eat more and feel less sick.
Warfarin is used to prevent and treat blood clots in your veins and lungs. It can also prevent clots if you have atrial fibrillation (irregular heartbeat) or a replacement heart valve. After a heart attack, it can lower the risk of death, another heart attack, or a stroke.
Dronabinol works by activating cannabinoid receptors in your brain. These receptors affect appetite, mood, and the sensation of nausea. By activating these receptors, dronabinol can increase appetite and reduce nausea and vomiting.
Warfarin works by blocking your body's use of vitamin K. Vitamin K is needed to make blood clotting factors. By blocking vitamin K, warfarin makes your blood less likely to clot.
- • Abdominal pain
- • Dizziness
- • Feeling very happy
- • Nausea
- • Feeling paranoid
- • Bleeding from any tissue or organ
- Nausea 878
- Fatigue 696
- Diarrhoea 604
- Death 593
- Vomiting 580
- International Normalised Ratio Increased 10,276
- Dyspnoea 8,408
- Drug Interaction 6,288
- Fatigue 6,143
- Nausea 5,921
Dronabinol can cause mental and mood changes. Tell your doctor if you have a history of mental illness. Do not drive or operate heavy machinery until you know how this medicine affects you. This medicine can also affect your heart, causing changes in blood pressure or heart rate. Dronabinol may also increase the risk of seizures.
Warfarin can cause major or fatal bleeding. You must have your blood tested regularly (INR) while taking warfarin. Many things, like other medicines and diet changes, can affect your INR. Tell your doctor about any bleeding and follow their instructions to prevent bleeding.
Dronabinol may harm your unborn baby. Avoid using this medicine if you are pregnant. If you are breastfeeding and have HIV, do not breastfeed due to the risk of passing HIV to your baby.
Warfarin can harm your unborn baby, especially during the first three months of pregnancy. Do not take warfarin if you are pregnant, unless you have a mechanical heart valve and your doctor says the benefits outweigh the risks. Talk to your doctor if you are breastfeeding, and watch your baby for bruising or bleeding.
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How to Read This dronabinol vs warfarin Comparison
dronabinol is classified in the Cannabinoid Antiemetic drug class, while warfarin sits within the Vitamin K Antagonist (Anticoagulant) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, dronabinol has 3,351 submissions while warfarin has 37,036. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to dronabinol can push warfarin off the proteins in your blood that normally hold it. this leaves more active warfarin in your system, which can increase the risk of bleeding.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for dronabinol or warfarin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.