digoxin vs telmisartan
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Side-by-side comparison of digoxin and telmisartan. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Digoxin: When telmisartan was co-administered with digoxin, median increases in digoxin peak plasma concentration (49%) and in trough concentration (20%) were observed. Therefore, monitor digoxin levels when initiating, adjusting, and discontinuing telmisartan for the purpose of keeping the digoxin level within the therapeutic range.
Lanoxin
Micardis
Digoxin (Lanoxin) is a medicine that helps your heart pump better. It is used to treat heart failure and control irregular heartbeats.
Telmisartan (Micardis) is a medicine that lowers blood pressure. It belongs to a class of drugs called angiotensin II receptor blockers (ARBs).
Digoxin is used to treat mild to moderate heart failure in adults. It helps the heart pump more blood with each beat. Digoxin is also used in children with heart failure to help their heart work better. In adults, it can control a fast and irregular heartbeat called atrial fibrillation.
Telmisartan is used to treat high blood pressure. Lowering blood pressure reduces the risk of strokes and heart attacks. It can also lower cardiovascular risk if you cannot take ACE inhibitors. Controlling high blood pressure is important for overall heart health.
Digoxin belongs to a class of drugs called cardiac glycosides. It works by making the heart muscle contract more strongly. It also slows down the electrical signals in the heart, which can help control irregular heartbeats.
Telmisartan blocks a substance in your body that tightens blood vessels. This helps blood vessels relax and widens them. As a result, blood pressure is lowered.
- • Nausea
- • Vomiting
- • Diarrhea
- • Dizziness
- • Headache
- • Back pain
- • Sinus infection
- • Diarrhea
- • Upper respiratory tract infection
- • Sore throat
- Dyspnoea 6,065
- Nausea 4,754
- Dizziness 4,439
- Fatigue 4,175
- Atrial Fibrillation 3,974
- Nausea 2,059
- Fatigue 2,001
- Diarrhoea 1,794
- Dyspnoea 1,785
- Headache 1,715
Digoxin can cause serious side effects, including dangerous heart rhythms. You are at higher risk if you have certain heart conditions or kidney problems. Tell your doctor right away if you have nausea, vomiting, vision changes, or an irregular heartbeat.
If you are pregnant or plan to become pregnant, stop taking this medicine right away. Telmisartan can harm or cause death to your unborn baby.
It is not known if digoxin can harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. The medicine passes into breast milk, but it is unlikely to harm the baby.
Telmisartan can cause harm to your unborn baby, especially during the second and third trimesters. Do not breastfeed while taking telmisartan.
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How to Read This digoxin vs telmisartan Comparison
digoxin is classified in the Cardiac Glycoside drug class, while telmisartan sits within the Angiotensin II Receptor Blocker (ARB) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, digoxin has 23,407 submissions while telmisartan has 9,354. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to telmisartan can raise the amount of digoxin in your blood by changing how your body processes and removes it.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for digoxin or telmisartan.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.