desloratadine vs erythromycin
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Side-by-side comparison of desloratadine and erythromycin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
7 DRUG INTERACTIONS 7.1 Inhibitors of Cytochrome P450 3A4 In controlled clinical studies co-administration of desloratadine with ketoconazole, erythromycin, or azithromycin resulted in increased plasma concentrations of desloratadine and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of desloratadine.
Clarinex
E-Mycin, Ery-Tab
Desloratadine is an antihistamine medicine. It helps relieve allergy symptoms.
Erythromycin Topical Solution is a medicine that you put on your skin to treat acne. It contains an antibiotic to help clear up your skin.
This medicine treats allergy symptoms. It can help with seasonal allergies like hay fever. It also treats year-round allergies and chronic hives by reducing itching and the number and size of hives.
Erythromycin Topical Solution treats acne vulgaris. This medicine helps to reduce acne on your face, neck, shoulders, chest, and back. It works by fighting the bacteria that cause acne.
Desloratadine blocks histamine in your body. Histamine is a substance that causes allergy symptoms. By blocking histamine, this medicine reduces those symptoms.
Erythromycin is a macrolide antibiotic. It works by stopping the growth of bacteria. This helps to reduce inflammation and clear up acne.
- • Sore throat
- • Dry mouth
- • Muscle pain
- • Tiredness
- • Sleepiness
- • Peeling
- • Dryness
- • Itching
- • Redness
- • Oily skin
- Fatigue 601
- Nausea 582
- Dyspnoea 532
- Headache 465
- Diarrhoea 448
- Drug Hypersensitivity 4,088
- Nausea 1,271
- Vomiting 1,121
- Diarrhoea 1,069
- Dyspnoea 1,023
Stop taking this medicine and get medical help right away if you have an allergic reaction. Signs of a reaction include rash, itching, hives, swelling, trouble breathing, or anaphylaxis.
You should not use this medicine if you are allergic to any of its ingredients.
Not enough studies have been done to know if desloratadine is safe during pregnancy. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if desloratadine passes into breast milk.
It is not known if erythromycin topical solution can harm an unborn baby. Talk to your doctor if you are pregnant or breastfeeding.
Also Compare, Nearby Drugs
Compare desloratadine with
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How to Read This desloratadine vs erythromycin Comparison
desloratadine is classified in the Second-Generation Antihistamine drug class, while erythromycin sits within the Macrolide Antibiotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, desloratadine has 2,628 submissions while erythromycin has 8,572. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to erythromycin interferes with the enzymes that process desloratadine, leading to higher-than-normal levels of the allergy drug in your body. these higher levels are generally considered safe and do not change how the drug works.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for desloratadine or erythromycin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.