cyclosporine vs oxaprozin
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Side-by-side comparison of cyclosporine and oxaprozin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Cyclosporine Clinical Impact: Concomitant use of COXANTO and cyclosporine may increase cyclosporine's nephrotoxicity. Intervention: During concomitant use of COXANTO and cyclosporine, monitor patients for signs of worsening renal function.
Neoral, Sandimmune, Restasis
Daypro
Vevye eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.
Oxaprozin (Daypro) is a nonsteroidal anti-inflammatory drug (NSAID). It helps to reduce pain and swelling.
Vevye treats the signs and symptoms of dry eye disease. Dry eye can cause discomfort, stinging, and blurred vision. This medicine can help reduce these symptoms.
This medicine can help with the symptoms of osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. These conditions can cause pain, swelling, and stiffness in your joints. Oxaprozin can help you feel better by reducing these symptoms.
Vevye contains cyclosporine, which is an immunosuppressant. It works by decreasing inflammation in the eyes. This helps your eyes make more tears.
Oxaprozin works by reducing substances in the body that cause pain and swelling. It blocks the production of prostaglandins. Prostaglandins contribute to inflammation and pain.
- • Irritation where the drops are applied (8%)
- • Constipation
- • Diarrhea
- • Upset stomach
- • Nausea
- • Rash
- Eye Irritation 7,786
- Pyrexia 4,064
- Eye Pain 3,808
- Nausea 3,623
- Diarrhoea 3,562
- Drug Hypersensitivity 386
- Pain 151
- Nausea 134
- Headache 104
- Arthralgia 103
To avoid eye injury or contamination, do not touch the bottle tip to your eye or any other surface. Do not use Vevye while wearing contact lenses. If you wear contacts, remove them before using the drops. You can put them back in 15 minutes after using Vevye.
NSAIDs like oxaprozin can increase your risk of heart problems like heart attack and stroke. This risk can happen early in treatment and may increase with longer use. You should not take this medicine if you are having heart bypass surgery. NSAIDs also increase the risk of stomach and intestine problems like bleeding and ulcers, which can be fatal. Older adults and people with a history of stomach ulcers are at higher risk.
It is not known if Vevye will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Cyclosporine can pass into breast milk after being taken orally, but it is unknown if it passes into breast milk from eye drops. Talk to your doctor if you are breastfeeding.
Taking oxaprozin after 20 weeks of pregnancy may harm your baby. Avoid taking this medicine after 30 weeks of pregnancy. Talk to your doctor if you are pregnant or plan to become pregnant.
Also Compare, Nearby Drugs
Compare oxaprozin with
How to Read This cyclosporine vs oxaprozin Comparison
cyclosporine is classified in the Calcineurin Inhibitor (Immunosuppressant) drug class, while oxaprozin sits within the Nonsteroidal Anti-Inflammatory Drug (NSAID) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, cyclosporine has 22,843 submissions while oxaprozin has 878. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to oxaprozin can increase the harmful effects that cyclosporine has on the kidneys. this occurs because both drugs can reduce the blood flow that helps the kidneys function properly.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for cyclosporine or oxaprozin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.