clarithromycin vs suvorexant
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Side-by-side comparison of clarithromycin and suvorexant. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
CYP3A Inhibitors Concomitant use of BELSOMRA with strong inhibitors of CYP3A (e.g., ketoconazole, itraconazole, posaconazole, clarithromycin, nefazodone, ritonavir, saquinavir, nelfinavir, indinavir, boceprevir, telaprevir, telithromycin and conivaptan) is not recommended [see Clinical Pharmacology (12.3) ].
Biaxin
Belsomra
Clarithromycin is an antibiotic that fights bacterial infections. It belongs to a class of drugs called macrolides.
Belsomra is a prescription medicine used to treat insomnia. It helps you fall asleep and stay asleep.
Clarithromycin treats mild to moderate infections caused by certain bacteria. It can treat bronchitis, sinus infections, pneumonia, and throat/tonsil infections. It also treats skin infections, ear infections in children, certain mycobacterial infections, and H. pylori infections that cause ulcers.
Belsomra is used to treat insomnia in adults. Insomnia means you have trouble falling asleep, staying asleep, or both. This medicine can help you sleep better.
Clarithromycin works by stopping the growth of bacteria. It prevents bacteria from making proteins they need to survive. This helps your body fight off the infection.
Belsomra works by blocking orexin, a chemical in your brain that keeps you awake. By blocking orexin, Belsomra helps to reduce wakefulness and allows you to fall asleep.
- • Abdominal pain
- • Diarrhea
- • Nausea
- • Vomiting
- • Taste changes
- • Sleepiness
- Drug Interaction 2,906
- Nausea 2,214
- Dyspnoea 1,959
- Diarrhoea 1,937
- Malaise 1,650
- Nightmare 736
- Somnolence 726
- Insomnia 674
- Abnormal Dreams 599
- Headache 535
Clarithromycin can cause severe allergic reactions. Stop taking it and get medical help right away if you have signs of a reaction. This medicine can also cause heart rhythm problems (QT prolongation) and liver problems. Tell your doctor if you have heart or liver issues. Clarithromycin may increase the risk of death in patients with coronary artery disease.
Belsomra can cause you to feel sleepy during the day and can impair your ability to drive. Do not drive or do other activities that require you to be fully alert, especially if you take the 20 mg dose. Belsomra may also worsen depression or cause suicidal thoughts. Tell your doctor right away if you have any new or worsening mood changes. Complex sleep behaviors like sleepwalking have also been reported. Stop taking Belsomra and tell your doctor if this happens.
Clarithromycin is not recommended during pregnancy unless there are no other options. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if clarithromycin passes into breast milk, so talk to your doctor before breastfeeding.
It is not known if Belsomra can harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if Belsomra passes into breast milk. Talk to your doctor about the best way to feed your baby if you take Belsomra.
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How to Read This clarithromycin vs suvorexant Comparison
clarithromycin is classified in the Macrolide Antibiotic drug class, while suvorexant sits within the Orexin Receptor Antagonist class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, clarithromycin has 10,666 submissions while suvorexant has 3,270. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to clarithromycin blocks the enzyme that breaks down suvorexant, which can cause the sleep medicine to build up to high levels in your body.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for clarithromycin or suvorexant.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.