ciprofloxacin vs cyclosporine
Side-by-side comparison of ciprofloxacin and cyclosporine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, enhance the effects of the oral anticoagulant, warfarin, and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving cyclosporine concomitantly.
Recommendation: Your healthcare provider should monitor your kidney function tests while you are on both medications.
Cipro
Neoral, Sandimmune, Restasis
Ciprofloxacin eye drops are an antibiotic medicine. They treat bacterial infections in the eye.
Vevye eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.
These eye drops treat corneal ulcers and conjunctivitis (pink eye) caused by certain bacteria. Corneal ulcers are open sores on the eye. Conjunctivitis is an infection that makes the eye red and swollen.
Vevye treats the signs and symptoms of dry eye disease. Dry eye can cause discomfort, stinging, and blurred vision. This medicine can help reduce these symptoms.
Ciprofloxacin is a fluoroquinolone antibiotic. It stops bacteria from growing and multiplying. This helps your body fight off the infection.
Vevye contains cyclosporine, which is an immunosuppressant. It works by decreasing inflammation in the eyes. This helps your eyes make more tears.
- • Burning or discomfort in the eye
- • White crystal-like build-up in the eye
- • Irritation where the drops are applied (8%)
- Allergic reaction to the medicine 5,673
- Pain 5,586
- Tiredness 5,504
- Diarrhea 5,328
- Feeling sick to your stomach 5,300
- Eye feels irritated 7,786
- Fever 4,066
- Eye ache 3,808
- Feeling sick to your stomach 3,623
- Loose stools 3,562
Do not inject this medicine into your eye. Some people have had very bad allergic reactions, even after the first dose. Get emergency help right away if you have trouble breathing, pass out, or have swelling of the face, throat, or tongue.
To avoid eye injury or contamination, do not touch the bottle tip to your eye or any other surface. Do not use Vevye while wearing contact lenses. If you wear contacts, remove them before using the drops. You can put them back in 15 minutes after using Vevye.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not known if ciprofloxacin eye drops will harm an unborn baby. It is also not known if ciprofloxacin passes into breast milk.
It is not known if Vevye will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Cyclosporine can pass into breast milk after being taken orally, but it is unknown if it passes into breast milk from eye drops. Talk to your doctor if you are breastfeeding.
Also Compare, Nearby Drugs
Compare ciprofloxacin with
How to Read This ciprofloxacin vs cyclosporine Comparison
ciprofloxacin is classified in the Fluoroquinolone Antibiotic drug class, while cyclosporine sits within the Calcineurin Inhibitor (Immunosuppressant) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, ciprofloxacin has 27,391 submissions while cyclosporine has 22,845. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to taking these two drugs together can cause a temporary increase in creatinine levels, which is a sign of stress on the kidneys.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between ciprofloxacin and cyclosporine - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.