cephalexin vs probenecid
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Side-by-side comparison of cephalexin and probenecid. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
( 7.1 ) Probenecid-The renal excretion of cephalexin is inhibited by probenecid. Co-administration of probenecid with cephalexin is not recommended. 7.2 Probenecid The renal excretion of cephalexin is inhibited by probenecid.
Keflex
Benemid
Cephalexin is an antibiotic medicine. It fights bacterial infections in your body.
No summary available.
Cephalexin treats infections caused by bacteria. It can treat infections in your lungs or airways. It also treats ear infections, skin infections, bone infections, and urinary tract infections.
Information not available.
Cephalexin belongs to a class of drugs called cephalosporins. It works by stopping the growth of bacteria. This helps your body fight off the infection.
Information not available.
- • Diarrhea
- • Nausea
- • Vomiting
- • Upset stomach
- • Stomach pain
- • Diarrhea
- • Nausea
- • Yeast infection of the vagina
- • Headache
- • Vomiting
- Chronic Kidney Disease 2,155
- Renal Failure 1,554
- Acute Kidney Injury 1,538
- Pain 1,365
- Diarrhoea 1,350
- Diarrhoea 76
- Dyspnoea 52
- Adenovirus Infection 47
- Asthenia 47
- Fatigue 46
Cephalexin can cause severe allergic reactions. Tell your doctor if you are allergic to penicillin or other cephalosporin antibiotics. This medicine can also cause severe diarrhea. If you get diarrhea, tell your doctor right away. People with kidney problems may need a lower dose to prevent seizures.
No specific warnings noted.
Tell your doctor if you are pregnant or breastfeeding. Studies haven't shown harm to the baby, but talk to your doctor about the risks and benefits. Cephalexin passes into breast milk, but the amount is very low.
No pregnancy information available.
Also Compare, Nearby Drugs
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How to Read This cephalexin vs probenecid Comparison
cephalexin is classified in the First-Generation Cephalosporin drug class, while probenecid sits within the Uricosuric Agent class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, cephalexin has 7,962 submissions while probenecid has 268. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to probenecid blocks your kidneys from removing cephalexin from your body. this causes the antibiotic to build up to higher levels than intended.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for cephalexin or probenecid.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.