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cefixime vs ceftazidime

Side-by-side comparison of cefixime and ceftazidime Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

Drug Class
cefixime Third-Generation Cephalosporin
ceftazidime Third-Generation Cephalosporin
Type
cefixime Prescription
ceftazidime Prescription
Summary
cefixime

Cefixime is an antibiotic that fights bacteria in your body. It is used to treat several different types of bacterial infections.

ceftazidime

Ceftazidime is an antibiotic medicine. It fights bacterial infections in your body.

What It Treats
cefixime

Cefixime treats infections like urinary tract infections, ear infections, and sore throats. It also treats bronchitis and gonorrhea. This medicine should only be used to treat infections that are proven or very likely to be caused by bacteria. This helps to prevent bacteria from becoming resistant to the medicine.

ceftazidime

Ceftazidime treats many kinds of infections caused by bacteria. This includes lung infections like pneumonia, skin infections, and urinary tract infections. It can also treat blood infections, bone and joint infections, and infections in the abdomen, the female reproductive system, and the brain (like meningitis).

How It Works
cefixime

Cefixime belongs to a class of drugs called cephalosporins. It works by stopping the growth of bacteria. This helps your body fight off the infection.

ceftazidime

Ceftazidime belongs to a class of drugs called cephalosporins. It works by stopping bacteria from building their cell walls. This kills the bacteria and clears the infection.

Common Side Effects
cefixime
  • Diarrhea (16%)
  • Nausea (7%)
  • Loose stools (6%)
  • Abdominal pain (3%)
  • Indigestion (3%)
ceftazidime
  • Pain or swelling where you got the shot
  • Rash
  • Itching
  • Fever
  • Diarrhea
FAERS Reports
cefixime
  • Drug Ineffective 276
  • Off Label Use 268
  • Pyrexia 162
  • Nausea 155
  • Diarrhoea 150
ceftazidime
  • Drug Ineffective 826
  • Off Label Use 657
  • Pyrexia 533
  • Septic Shock 335
  • Condition Aggravated 319
Serious Warnings
cefixime

Cefixime can cause severe allergic reactions, including shock and death. Stop taking cefixime and get medical help right away if you have any signs of an allergic reaction. Cefixime can also cause severe diarrhea due to a bacteria called Clostridium difficile. Tell your doctor right away if you have diarrhea while taking cefixime.

ceftazidime

Ceftazidime can cause a type of diarrhea called pseudomembranous colitis. Tell your doctor right away if you have severe stomach pain or bloody diarrhea. This can happen during or after treatment.

Pregnancy
cefixime

Tell your doctor if you are pregnant or plan to become pregnant. Studies haven't shown harm to the fetus, but it's important to discuss the risks and benefits with your doctor. It is not known whether cefixime passes into breast milk.

ceftazidime

Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not fully known if ceftazidime will harm your unborn baby or pass into breast milk.

Also Compare — Nearby Drugs

How to Read This cefixime vs ceftazidime Comparison

cefixime is classified in the Third-Generation Cephalosporin drug class, while ceftazidime sits within the Third-Generation Cephalosporin class. Because both drugs share the same classification, they are often considered interchangeable in theory — but clinical outcomes rarely track that cleanly. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, cefixime has 1,011 submissions while ceftazidime has 2,670. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between cefixime and ceftazidime — always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.