Skip to main content

Two medicines, side by side

Cefadroxil vs cefdinir

Cefadroxil and cefdinir are both labeled for bacterial infections. Pharmacies paid $0.269 per cefadroxil 500 mg capsule and $0.458 per cefdinir 300 mg capsule (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like.

Check it at the source: the cefadroxil FDA label on DailyMed (effective June 1, 2026); the cefdinir FDA label on DailyMed (effective October 14, 2025).

Highlights of the cefadroxil record

Cefadroxil · label of June 1, 2026

Used for

From the label: indications

Cefadroxil Capsules USP are indicated for the treatment of patients with infection caused by susceptible strains of the designated organisms in the following diseases: Urinary tract infections caused by E. coli, P. mirabilis, and Klebsiella species. Skin and skin structure infections caused by staphylococci and/or streptococci. […]

On the market

Earliest approval on file
n/a
Generic labelers
19 labelers
Pharmacy cost
$0.269 per capsule

Supply and safety

Shortage
No current entry
Recalls
0

Highlights of the cefdinir record

Cefdinir (Omnicef) · label of October 14, 2025

Used for

From the label: indications

To reduce the development of drug-resistant bacteria and maintain the effectiveness of cefdinir capsules and other antibacterial drugs, cefdinir capsules should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. […]

On the market

Earliest approval on file
December 4, 1997
Generic labelers
26 labelers
Pharmacy cost
$0.458 per capsule

Supply and safety

Shortage
No current entry
Recalls
11

Source: FDA drug labels via openFDA (Cefadroxil label of June 1, 2026, Cefdinir label of October 14, 2025); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do cefadroxil and cefdinir differ on the record?

Both are in FDA's class cephalosporin antibacterials.

Generics: cefadroxil none approved; cefdinir since 2006 (Drugs@FDA).

CefadroxilCefdinir
Labeled forBacterial infections, Urinary tract infectionsBacterial infections
Pharmacologic classCephalosporin AntibacterialCephalosporin Antibacterial
How it works (label)n/an/a
Half-life (label)n/an/a
Earliest approval on file (Drugs@FDA)n/aDecember 4, 1997
First generic approvednoneMay 19, 2006
Generic labelers (NDC)19 labelers26 labelers
Pharmacy cost (NADAC, each one's most listed form; strengths differ)$0.269 per capsule (Cefadroxil 500 mg capsule)$0.458 per capsule (Cefdinir 300 mg capsule)
12-month price change-9%+0.7%
Boxed warningNoNo
Shortage nowNo current entryNo current entry
Recalls recorded011
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)1,9807,628
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to cefadroxil
every medicine labeled for the same conditions