carvedilol vs fluconazole
Side-by-side comparison of carvedilol and fluconazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
The concomitant administration of amiodarone or other CYP2C9 inhibitors such as fluconazole with carvedilol may enhance the β-blocking activity, resulting in further slowing of the heart rate or cardiac conduction.
Recommendation: Your doctor may need to watch your heart rate and adjust your medication if it becomes too slow.
Coreg
Diflucan
Carvedilol is a medicine that lowers blood pressure and helps your heart work better. It belongs to a class of drugs called alpha/beta-blockers.
Fluconazole is an antifungal medicine. It is used to treat infections caused by fungus.
Carvedilol treats a few different heart conditions. It is used for long-term heart failure to help you live longer and go to the hospital less. It also helps people who had a heart attack and have a weak heart pump. Carvedilol can also treat high blood pressure.
Fluconazole treats vaginal yeast infections. It also treats yeast infections in the mouth and esophagus. Fluconazole can also treat urinary tract infections, peritonitis, systemic Candida infections, and pneumonia. It can also treat cryptococcal meningitis. Fluconazole can also prevent candidiasis in patients undergoing bone marrow transplantation.
Carvedilol works by blocking the effects of certain natural chemicals in your body, such as adrenaline. This helps to relax blood vessels and slows down your heart rate. As a result, it lowers blood pressure and makes it easier for your heart to pump blood.
Fluconazole works by stopping the growth of fungi. It blocks the fungus from producing a substance it needs to grow. This helps to clear up the infection.
- • Dizziness
- • Tiredness
- • Low blood pressure
- • Diarrhea
- • High blood sugar
- • Headache
- • Nausea
- • Abdominal pain
- Tiredness 8,668
- Difficulty breathing 8,176
- Diarrhea 6,867
- Dizziness 6,776
- Feeling sick to your stomach 6,489
- Fever 4,121
- Feeling sick to your stomach 3,695
- Loose stools 3,536
- Feeling tired 3,152
- Discomfort 3,121
Do not stop taking carvedilol suddenly if you have heart problems. This can make chest pain worse and may cause a heart attack. If you need to stop taking carvedilol, your doctor will slowly lower your dose over 1 to 2 weeks. Carvedilol can also cause your heart rate to slow down too much or lower your blood pressure too much. If your pulse rate drops below 55 beats per minute, talk to your doctor about lowering the dose.
Coadministration of other drugs known to prolong the QT interval and which are metabolized via the enzyme CYP3A4 such as erythromycin, pimozide, and quinidine are contraindicated in patients receiving fluconazole.
It is not known if carvedilol will harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Beta-blockers like carvedilol may cause low blood pressure, slow heart rate, and breathing problems in newborns.
Tell your doctor if you are pregnant or plan to become pregnant. Fluconazole may not be safe for your baby. Talk to your doctor about breastfeeding while taking fluconazole.
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How to Read This carvedilol vs fluconazole Comparison
carvedilol is classified in the Beta-Blocker (Alpha/Beta) drug class, while fluconazole sits within the Azole Antifungal class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, carvedilol has 36,976 submissions while fluconazole has 17,625. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to fluconazole prevents the body from breaking down carvedilol properly. this leads to higher levels of the drug in your system, which can slow your heart rate too much.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between carvedilol and fluconazole - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.