carbamazepine vs ethinyl estradiol/norgestimate

PlainMeds reviewed this comparison against our methodology in August 2026. It places FDA and CMS record fields side by side, without recommending either medication.

Side-by-side comparison of carbamazepine and ethinyl estradiol/norgestimate. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Examples Aprepitant, barbiturates, bosentan, carbamazepine, efavirenz, felbamate, griseofulvin, oxcarbazepine, phenytoin, rifampin, rifabutin, rufinamide, topiramate, products containing St.

Drug Class
carbamazepine Anticonvulsant
ethinyl estradiol/norgestimate Combined Oral Contraceptive
Type
carbamazepine Prescription
ethinyl estradiol/norgestimate Prescription
Summary
carbamazepine

Carbamazepine is a medicine used to control seizures and treat nerve pain. It works by reducing abnormal electrical activity in the brain and calming nerve signals.

ethinyl estradiol/norgestimate

Iclevia is a birth control pill. It contains two hormones, levonorgestrel and ethinyl estradiol, to prevent pregnancy.

What It Treats
carbamazepine

Carbamazepine is used to treat certain types of seizures, including partial seizures and generalized tonic-clonic seizures. It can also treat mixed seizure patterns. Carbamazepine also treats the pain from trigeminal neuralgia, a nerve disorder that causes intense facial pain. It is also sometimes used for glossopharyngeal neuralgia.

ethinyl estradiol/norgestimate

Iclevia is used by women who can get pregnant to prevent pregnancy. It contains two hormones, a progestin and an estrogen. These hormones work together to prevent ovulation and change the lining of the uterus.

How It Works
carbamazepine

Carbamazepine is an anticonvulsant. It works by reducing the spread of seizure activity in the brain. It also stabilizes nerve impulses to reduce pain.

ethinyl estradiol/norgestimate

Iclevia contains two hormones: levonorgestrel and ethinyl estradiol. These hormones prevent ovulation (the release of an egg from the ovary). They also change the lining of the uterus, making it harder for a fertilized egg to implant.

Common Side Effects
carbamazepine
  • Dizziness
  • Drowsiness
  • Unsteadiness
  • Nausea
  • Vomiting
ethinyl estradiol/norgestimate
  • Headache
  • Heavier menstrual bleeding
  • Nausea
  • Painful periods
  • Acne
FAERS Reports
carbamazepine
  • Seizure 3,609
  • Drug Interaction 3,369
  • Fall 3,044
  • Dizziness 2,862
  • Pyrexia 2,689
ethinyl estradiol/norgestimate

No adverse event reports.

Serious Warnings
carbamazepine

Carbamazepine can cause severe skin reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), which can be fatal. If you are of Asian descent, you may need a blood test before starting this medicine. Carbamazepine can also cause serious blood problems like aplastic anemia and agranulocytosis. Contact your doctor right away if you develop a fever, sore throat, rash, or unusual bleeding or bruising.

ethinyl estradiol/norgestimate

Cigarette smoking increases your risk of serious heart problems from birth control pills. This risk is higher if you are over 35 and smoke more cigarettes. If you are over 35 and smoke, you should not take Iclevia.

Pregnancy
carbamazepine

Carbamazepine may harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if carbamazepine passes into breast milk, so talk to your doctor about breastfeeding.

ethinyl estradiol/norgestimate

Do not use Iclevia if you are pregnant. Iclevia can reduce milk production while breastfeeding, so another form of birth control is recommended. Talk to your doctor about the best option for you.

Also Compare, Nearby Drugs

How to Read This carbamazepine vs ethinyl estradiol/norgestimate Comparison

carbamazepine is classified in the Anticonvulsant drug class, while ethinyl estradiol/norgestimate sits within the Combined Oral Contraceptive class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, carbamazepine has 15,573 submissions while ethinyl estradiol/norgestimate has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to carbamazepine speeds up how your body breaks down birth control hormones, which can make the pill less effective at preventing pregnancy.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for carbamazepine or ethinyl estradiol/norgestimate.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.