Two medicines, side by side
Bisacodyl vs polyethylene glycol 3350
Bisacodyl and polyethylene glycol 3350 are both labeled for constipation. Pharmacies paid $0.320 per bisacodyl 10 mg suppository and $0.0286 per gram (Polyethylene glycol 3350 powd) (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like.
Check it at the source: the bisacodyl FDA label on DailyMed (effective April 8, 2025); the polyethylene glycol 3350 FDA label on DailyMed (effective May 4, 2026).
Highlights of the bisacodyl record
Bisacodyl · label of April 8, 2025
Used for
From the label: indications● for relief of occasional constipation and irregularity ● this product generally produces bowel movement in 6 to 12 hours Use ● for relief of occasional constipation and irregularity ● this product generally produces bowel movement in 6 to 12 hours
On the market
- Earliest approval on file
- n/a
- Generic labelers
- none listed
- Pharmacy cost
- $0.320 per suppository
Supply and safety
- Shortage
- No current entry
- Recalls
- 0
Highlights of the polyethylene glycol 3350 record
Polyethylene glycol 3350 (Miralax) · label of May 4, 2026
Used for
From the label: indicationsrelieves occasional constipation (irregularity) generally produces a bowel movement in 1 to 3 days
On the market
- Earliest approval on file
- February 18, 1999
- Generic labelers
- 69 labelers
- Pharmacy cost
- $0.0286 per gram
Supply and safety
- Shortage
- No current entry
- Recalls
- 4
Source: FDA drug labels via openFDA (Bisacodyl label of April 8, 2025, Polyethylene glycol 3350 label of May 4, 2026); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)
How do bisacodyl and polyethylene glycol 3350 differ on the record?
Generics: bisacodyl none approved; polyethylene glycol 3350 since 2004 (Drugs@FDA).
| Bisacodyl | Polyethylene glycol 3350 | |
|---|---|---|
| Labeled for | Constipation | Constipation |
| Pharmacologic class | n/a | Osmotic Laxative |
| How it works (label) | n/a | n/a |
| Half-life (label) | n/a | n/a |
| Earliest approval on file (Drugs@FDA) | n/a | February 18, 1999 |
| First generic approved | none | July 2, 2004 |
| Generic labelers (NDC) | none listed | 69 labelers |
| Pharmacy cost (NADAC, each one's most listed form; strengths differ) | $0.320 per suppository (Bisacodyl 10 mg suppository) | $0.0286 per gram (Polyethylene glycol 3350 powd) |
| 12-month price change | -4% | -1% |
| Boxed warning | No | No |
| Shortage now | No current entry | No current entry |
| Recalls recorded | 0 | 4 |
| FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used) | 14,161 | 105,254 |
| DEA schedule | none | none |
Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)
What next?
- Alternatives to bisacodyl
- every medicine labeled for the same conditions