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Two medicines, side by side

Bisacodyl vs glycerin

Bisacodyl and glycerin are both labeled for constipation. Pharmacies paid $0.320 per bisacodyl 10 mg suppository and $0.103 per glycerin suppository (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like.

Check it at the source: the bisacodyl FDA label on DailyMed (effective April 8, 2025); the glycerin FDA label on DailyMed (effective October 29, 2025).

Highlights of the bisacodyl record

Bisacodyl · label of April 8, 2025

Used for

From the label: indications

● for relief of occasional constipation and irregularity ● this product generally produces bowel movement in 6 to 12 hours Use ● for relief of occasional constipation and irregularity ● this product generally produces bowel movement in 6 to 12 hours

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.320 per suppository

Supply and safety

Shortage
No current entry
Recalls
0

Highlights of the glycerin record

Glycerin · label of October 29, 2025

Used for

From the label: indications

for relief of occasional constipation this product generally produces a bowel movement in 1/4 to 1 hour

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.103 per suppository

Supply and safety

Shortage
No current entry
Recalls
0

Source: FDA drug labels via openFDA (Bisacodyl label of April 8, 2025, Glycerin label of October 29, 2025); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do bisacodyl and glycerin differ on the record?

BisacodylGlycerin
Labeled forConstipationConstipation, Herpes and shingles
Pharmacologic classn/an/a
How it works (label)n/an/a
Half-life (label)n/an/a
Earliest approval on file (Drugs@FDA)n/an/a
First generic approvednonenone
Generic labelers (NDC)none listednone listed
Pharmacy cost (NADAC, each one's most listed form; strengths differ)$0.320 per suppository (Bisacodyl 10 mg suppository)$0.103 per suppository (Glycerin suppository)
12-month price change-4%-7%
Boxed warningNoNo
Shortage nowNo current entryNo current entry
Recalls recorded00
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)14,1615,822
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to bisacodyl
every medicine labeled for the same conditions