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Two medicines, side by side

Bisacodyl vs docusate

Bisacodyl and docusate are both labeled for constipation. Pharmacies paid $0.320 per bisacodyl 10 mg suppository and $0.0276 per unit (Docusate sodium 100 mg softgel) (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like.

Check it at the source: the bisacodyl FDA label on DailyMed (effective April 8, 2025); the docusate FDA label on DailyMed (effective February 6, 2025).

Highlights of the bisacodyl record

Bisacodyl · label of April 8, 2025

Used for

From the label: indications

● for relief of occasional constipation and irregularity ● this product generally produces bowel movement in 6 to 12 hours Use ● for relief of occasional constipation and irregularity ● this product generally produces bowel movement in 6 to 12 hours

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.320 per suppository

Supply and safety

Shortage
No current entry
Recalls
0

Highlights of the docusate record

Docusate · label of February 6, 2025

Used for

From the label: indications

relieves occasional constipation (irregularity) generally produces bowel movement in 12 to 72 hours

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.0276 per unit

Supply and safety

Shortage
No current entry
Recalls
2

Source: FDA drug labels via openFDA (Bisacodyl label of April 8, 2025, Docusate label of February 6, 2025); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do bisacodyl and docusate differ on the record?

BisacodylDocusate
Labeled forConstipationConstipation
Pharmacologic classn/an/a
How it works (label)n/an/a
Half-life (label)n/an/a
Earliest approval on file (Drugs@FDA)n/an/a
First generic approvednonenone
Generic labelers (NDC)none listednone listed
Pharmacy cost (NADAC, each one's most listed form; strengths differ)$0.320 per suppository (Bisacodyl 10 mg suppository)$0.0276 per unit (Docusate sodium 100 mg softgel)
12-month price change-4%-5%
Boxed warningNoNo
Shortage nowNo current entryNo current entry
Recalls recorded02
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)14,16158,569
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to bisacodyl
every medicine labeled for the same conditions